Coexistence of tuberculosis and squamous cell carcinoma in the right main bronchus: A case report

Figure 1 Bronchoscopic images of the main carina. A: Tumorous endobronchial lesion located in the right main bronchus; B: After removal of the right main mass.

Figure 2 Bronchial biopsy. A: Granulomatous inflammation with caseification, which is consistent with tuberculosis (Hematoxylin and eosin stain, × 200); B: Biopsy staining showed positivity for acid-fast bacilli (Ziehl-Nielsen staining, × 1000).

Figure 3 Imaging changes of the mass before treatment. A: Reconstructed thoracic computed tomography (CT) image; B: Enhanced chest CT in mediastinal window; C: Axial CT in lung window showing narrowing of the main bronchus and airspace consolidation in the right bronchus, without parenchymal infiltration or pneumonia.

Figure 4 Chest computed tomography images (December 23, 2019) showing a 5 mm × 4 mm lung mass in the right main bronchus. A: Lung window; B: Mediastinal window.

Figure 5 Bronchoscopy (December 23, 2019). A and B: A black mucosa was found in the right main bronchus.

Figure 6 Histological and immunohistochemical examinations. A: The right main bronchus mass was squamous cell carcinoma (hematoxylin and eosin staining, × 200); B: The tumor cells were positive for P63, P40, CK7, CK(Pan), Ki67, and p53 but negative for TTF-1, NapsinA, SOX2, SALL4, and CD34 (× 200).

Figure 7 Chest computed tomography images (March 20, 2020) showing complete resolution of the lesion in the right main bronchus. A: Lung window; B: Mediastinal window.