Diagnosis and treatment of pediatric anaplastic lymphoma kinase-positive large B-cell lymphoma: A case report

Figure 1 Tumor cells found in bone marrow smears (Wright-Giemsa-stained, 1000 ×).

Figure 2 Positron emission tomography/computed tomography scan. A: Trunk; B: Cranium.

Figure 3 Hematoxylin and eosin-stained section of neck lymph node biopsy (200 ×). A: Positive cluster of differentiation 31 staining; B: Positive friend leukemia integration 1 staining; C: Positive anaplastic lymphoma kinase staining; D: Positive leukocyte-common antigen staining; E: Positive multiple myeloma oncogene 1 staining; F: Positive immunoglobulin A staining.

Figure 4 Fluorescence in situ hybridization study with ALK breakapart probe showed ALK gene disruption.

Figure 5 CLTC-ALK fusion-positive in bone marrow.