Metachronous pulmonary and pancreatic metastases arising from sigmoid colon cancer: A case report

Figure 1 Course of disease management for the case described in this report.

Figure 2 Positron emission tomography/computed tomography scan showing pathological hypermetabolism in the head of the pancreas. No abnormalities were noted in the stomach, duodenum, common bile duct, or main pancreatic duct.

Figure 3 Representative results of hematoxylin and eosin and immunohistochemical staining of specimens from primary and metastatic lesions. A-L: In the primary sigmoid adenocarcinoma, H&E staining (A) and CK20⁺ (B), CK7^- (C), and CDX2⁺ (D) with IHC were similar to findings in lung metastasis (E-H) of CK20⁺ (F), CK7^- (G), and CDX2⁺ (H). In addition, the pancreatic metastasis (I-L) also displayed biomarker expression profile consistent with colon cancer as the tissue of origin. H&E: Hematoxylin and eosin; IHC: Immunohistochemical.