Recalcitrant paradoxical pustular psoriasis induced by infliximab: Two case reports

Figure 1 Case 1. A-C: Generalized erythema and plaques with obvious red halos and oyster-like scales. Some lesions have many pustules; D-F: (hematoxylin and eosin, × 40, × 200, and × 400) Psoriasiform hyperplasia and mild spongiosis with focal hypogranulosis and parakeratosis containing neutrophilic debris; G-I: Lesions before, and after the first and second secukinumab administration; J-L: Lesions before, and 1 and 3 wk after colchicine treatment.

Figure 2 Case 2. A-C: Red papules and plaques on the trunk and limbs showing desquamation. Yellow pustules can be seen on the palms and soles, some of which are dried up and have brown yellow crusts; D-F: hematoxylin and eosin, × 200, × 40, and × 400) Psoriasiform hyperplasia with subcorneal pustules; G-I: Hands and feet after ustekinumab treatment.