Misdiagnosed dystrophic epidermolysis bullosa pruriginosa: A case report

Figure 1 Physical examination. A-C: Clinical findings at the first visit. Multiple symmetric papules and nodules involving both calves (A); violet and hyperpigmented papules and nodules on the left calf with surface excoriations (B); and skin-colored papules and nodules on the back (C); D-F: The initial clinical findings on both calves were resolved after treatment. Flattening of the lesion on the right calf and reduced number of lesions on both sides after treatment (D); flattened and pale nodules on the left calf (E); the lesions on the right calf almost disappeared (F).

Figure 2 Histopathological findings from the left calf erosion (hematoxylin-eosin, original magnification × 20). A: Hyperkeratosis and subepidermal cleft with moderate inflammatory infiltrate in the upper dermis showing scar tissue formation; B: The dermis revealed round keratin cysts with chronic inflammatory infiltrates in the upper dermis.