Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report

Figure 1 Chest computed tomography scan at admission. A: Multiple masses and nodules were found in both lungs; B: Multiple consolidation in both lungs; C: No obvious enhancement was found in the nodules; D: Hilar and mediastinal lymphadenopathy.

Figure 2 Imaging changes in the lung after anti-tuberculosis treatment. A: The pulmonary nodules were larger than before treatment; B: The lung shadow was greater than before treatment.

Figure 3 Results of bronchoscopic biopsy. A: Biopsies revealed local granulomatous structure; peripheral fibrous hyperplasia; lymphocyte, plasma cell and neutrophil infiltration (Papanicolaou stain, 20 ×); B: By microscopy, columnar epithelial cells and individual lymphocytes were seen, and no heterotypic cells were found (hematoxylin and eosin stain, 20 ×).

Figure 4 Chest computed tomography scan re-examination at the last follow-up on May 6, 2020. A: There were strip shadows in both lungs; B: No obvious shadow or nodules were found in both lungs.