Primary lung cancer with radioiodine avidity: A thyroid cancer cohort study

Figure 1 Flow chart of cohort establishment. ¹Including lymphoma, squamous cell carcinoma, leiomyosarcoma, lymphoepithelioma-like carcinoma, teratoma, and metastatic cancer to the thyroid. NSCLC-NOS: Non-small cell lung carcinoma-not otherwise specified.

Figure 2 Details of patient 1. A: Radioiodine scan was performed 7 d after oral administration of 30 mCi iodine-131. Radioiodine uptake was identified in the right chest (black arrow); B: Computed tomography revealed a single 1.7-cm spiculated nodule in the right upper lobe (orange arrow); C: Fused single-photon emission computed tomography/computed tomography imaging demonstrated a focal area of radioiodine activity in the right lung tumor (orange arrow); D: ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography showed that the lung tumor was ^18FFDG avid (orange arrow); E: Histopathologic features of the right lung tumor were consistent with lung adenocarcinoma (hematoxylin and eosin staining, 200 ×); F: Immunostaining for sodium/iodide symporter (NIS) showed NIS expression in lung adenocarcinoma cells (brown; 200 ×).