Late-onset non-islet cell tumor hypoglycemia: A case report

Figure 1 Imaging findings. A and B: Chest X-ray (A) and computed tomography (B) (left-hand side is transverse plane; right-hand side is coronal plane) showed a heterogenous giant mass measuring 11 cm × 14 cm × 15 cm in size on the right lower chest; C: Computed tomography from ten years ago showed the tumor’s growth in the past decade; D and E: Positron emission tomography (D) and octreotide scintigraphy (E) showed the tumor’s accumulation.

Figure 2 Pathological findings. A: Western blot analysis of high-molecular-weight insulin-like growth factor II (IGF-II). High molecular weight form of IGF-II was detected, both in the tumor tissue and in the serum; B: Histopathological examination of biopsy specimens. The tumor cells were immunopositive for IGF-II. The upper panel shows macroscopic findings of the surgical specimen. HE, hematoxylin and eosin staining; IGF-II, immunohistochemical staining for IGF-II; C: The tumor size was 15.6 cm × 13.7 cm × 10.4 cm. The histological diagnosis was of a solitary fibrous tumor. Histopathological characteristics were as follows: CD34:(-), STAT6(+), c-kit(-), S-100:(-), desmin:(-), αSMA(-), p53(±), and MIB-1: 3.6%. HE: Hematoxylin and eosin; IGF-II: Insulin-like growth factor II.