Multiple neurofibromas plus fibrosarcoma with familial NF1 pathogenicity: A case report

Figure 1 Multiple subcutaneous nodules throughout the body. A: Two subcutaneous nodules in the forehead; B: Subcutaneous nodule on the middle phalanx of the left hand; C: Pigmentation on the right hypochondrium of the torso.

Figure 2 Changes in the patient’s tumor size from day 1 to day 24 after hospitalization. A: A large mass in the right thoracic cavity, accompanied by extensive hydrothorax on the same side; B: Tumor growth in the right thoracic cavity was obvious, while the hydrothorax was significantly reduced after treatment.

Figure 3 Microscopic findings show neurofibrosarcoma. A: Abnormal hyperplasia of high chromatin cells (immunohistochemistry, × 100); B: Abnormally proliferating spindle cells (immunohistochemistry, × 400).