Combining surgery with 125I brachytherapy for recurrent mediastinal dedifferentiated liposarcoma: A case report and review of literature

Figure 1 Imaging findings. A and B: Chest contrast-enhanced computed tomography scans showed several cystic-solid encapsulated masses in posterior-inferior mediastinum with well-defined margins, fatty density, soft tissue density, calcification and slight enhancement; C: 18F-fluorodeoxyglucose PET showed the maximum standardized uptake value (SUVave) of 1.8.

Figure 2 Pathological findings. A: Gross appearance showed the largest tumor was about 105 mm × 94 mm × 88 mm in size, and the smallest was about 20 mm in diameter; the tumors had integrated capsules; B and C: H&E staining showed a well-differentiated liposarcoma component and spindle cell component (× 100 and × 200, respectively); C: Immunohistochemical analysis showed the tumor was positive for S-100 protein in scattered cells (× 200).