Erdheim-Chester disease with asymmetric talus involvement: A case report

Figure 1 Histopathological findings of the lesions (100 ×). A: Hematoxylin-eosin stains of the specimen; B: Immunohistochemistry showing positive staining for CD68; C: Immunohistochemistry showing positive staining for ACTT; D: Immunohistochemistry showing negative staining for CD34; E: Immunohistochemistry showing negative staining for S100; F: Immunohistochemistry showing negative staining for CD1a.

Figure 2 Plain X-ray film taken 5 years ago showed slight osteosclerosis in the tibia and the talus (white arrow).

Figure 3 Plain anteroposterior radiography of the tibiofibula indicated osteosclerosis in the tibia and osteolytic lesions in the talus (arrow).

Figure 4 Computed tomography clearly suggested the left talus osteolytic destruction and cortical discontinuity of the anterior articular surface (white arrow).

Figure 5 Magnetic resonance imaging showed osteolytic lesions in the talus hypointense on T1WI and hyperintense on T2WI (white arrow).

Figure 6 Magnetic resonance imaging suggested a marrow-replacing infiltrative lesion of the tibia hypointense on T1WI and hyperintense on T2WI.

Figure 7 Comparison of preoperative and postoperative whole-body bone scans.

Figure 8 Computed tomography showed that lesions in the talus were completely removed and the bone was filled with cement casting.

Figure 9 Postoperative plain X-rays indicated complete lesion removal and no signs of recurrence.