Radiation recall dermatitis with dabrafenib and trametinib: A case report

Figure 1 One month after completion of radiotherapy, discolored and inflamed skin limited to the region previously irradiated was observed while being treated with BRAF and MEK inhibitor combination therapy. A: Front view of right leg-discolored and inflamed skin limited to the region previously irradiated; B: Back view of right leg-discolored and inflamed skin limited to the region previously irradiated; C: Front view of right leg; D: Back view of right leg.

Figure 2 Similar lesions on the opposite leg.

Figure 3 A dermal biopsy was performed and orthokeratotic epidermis with lymphocytic infiltration was observed in the pathologic specimen. A: Perivascular lymphocytes (Hematoxylin-eosin staining, × 20); B: Perivascular lymphocytes (Hematoxylin-eosin staining, × 20).