Epidermolytic acanthoma: A case report

Figure 1 External inspection of the anus demonstrates a pale colored papule three millimeters in size located one centimeter from the anal verge at the right anterior position (left panel). Magnified view of the lesion with high high resolution anoscopy shows a smooth, well-demarcated perianal lesion (right panel). The right panel shows the same lesion as the left panel at a higher magnification. The magnified photo was taken through a clear anoscope that was used to flatten out the perianal skin folds. The shine is a result of the lubricating gel.

Figure 2 Hematoxylin and eosin photomicrographs of the leison. The left panel demonstrates compact hyperkeratosis (yellow star) and acanthosis (orange arrow), with the formation of keratin crypts. Higher magnification (right panel) shows intracellular vacuolar degeneration of the epithelial cells of the spinous cell layer, as indicated by the orange arrows.