Majocchi's granuloma caused by Trichophyton rubrum after facial injection with hyaluronic acid: A case report

Figure 1 Physical examination. A: Before treatment; B: After oral itraconazole for 8 wk.

Figure 2 Histologic examination of the skin lesion demonstrated diffuse suppurative and granulomatous inflammation. The diffuse infiltration of lymphocytes, histiocytes, and multinucleated giant cells was observed in the dermis. A: Fungal mycelium was clearly observed in a giant cell (Hematoxylin-eosin staining, × 400); B: Several giant cells and macrophages were stained with periodic acid-Schiff (Hematoxylin-eosin staining, × 1000).

Figure 3 Mycology examinations. A white and dark red colony was observed.

Figure 4 Deoxyribonucleic acid sequence alignment of isolated Trichophyton rubrum and Centraalbureau voor Schimmelcultures 189. 69. CBS: Centraalbureau voor Schimmelcultures.