Effective combined therapy for pulmonary epithelioid hemangioendothelioma: A case report

Figure 1 ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography. A: ¹⁸F-fluorodeoxyglucose positron emission tomography shows abnormal accumulation of fluorodeoxyglucose throughout the chest, with no other significant findings in the body; B-D: Computed tomography scan of the thorax reveals multiple pulmonary nodules with different sizes.

Figure 2 Comparison of chest images before and after treatment. A: Chest computed tomography (CT) scan on lung window shows diffusely scattered, round, non-calcified nodules in both lungs before treatment; B and C: CT scans at the 8-mo follow-up (B) and 24-mo follow-up (C) after combined treatment. CT image demonstrates stabilization of bilateral multiple nodules both in size and density.

Figure 3 Immunohistochemical findings. A: Tumor cells, in a short strip form and with epithelial cell features, have no nuclear division and contain abundant eosinophils in the cytoplasm (× 20). B and C: Immunohistochemical analyses for CD34 (B) and CD31 (C) are positive both in the cytoplasm and the tumor cell membrane (× 40); D: Immunohistochemical analysis for Vimentin reveals positivity in the cytoplasm (× 40).