Heterotopic pancreas adenocarcinoma in the stomach: A case report and literature review

Figure 1 Radiologic and endoscopic features of the tumor. A: Gastroscopy showed a nodular protruding lesion at the gastric antrum and stenosis of the pyloric ring; B: Abdominal computed tomography showed that the wall of the antrum was thickened and enhanced (arrow); C: Barium meal examination showed filling defect at the antrum and stenosis of the lumen.

Figure 2 Hematoxylin-eosin histopathological examination of the surgically resected specimen. A: A well-differentiated adenocarcinoma was revealed, coexisting with pancreatic heterotopia composed of ducts (×100); B: High-power view of duct-like structures of adenocarcinoma (×400); C: Invasion of bundles of nerves was seen (arrow) (×200).

Figure 3 Immunohistochemical staining. A: Cytokeratin 7 (×200); B: Carcinoembryonic antigen (×200); C: CDX-2 (×400); D: Cytokeratin 20 (×200).