Changes of serum inflammatory factors and miR-145 expression in patients with osteoarthritis before and after treatment and their clinical value

Figure 1 Expression levels of miR-145 in the peripheral blood of the two groups. ^aP < 0.05.

Figure 2 Levels of inflammatory factors in peripheral blood between the two groups. ^aP < 0.05.

Figure 3 Correlation of miR-145 and inflammatory factors with VAS scores. VAS scores were positively correlated with miR-145, TNF-α, and IL-6, and negatively correlated with IL-10 (P < 0.05). TNF: Tumor necrosis factor; IL: Interleukin.

Figure 4 Relationship of miR-145 and inflammatory factors with Lysholm scores. Lysholm scores were negatively correlated with miR-145, TNF-α, and IL-6, and positively correlated with IL-10 (P < 0.05). TNF: Tumor necrosis factor; IL: Interleukin.

Figure 5 Correlation of miR-145 and inflammatory factors with WOMAC scores. WOMAC scores were positively correlated with miR-145, TNF-α, and IL-6 (P < 0.05), and negatively correlated with IL-10 (P < 0.05). TNF: Tumor necrosis factor; IL: Interleukin.

Figure 6 Correlation of miR-145 and inflammatory factors with Kellgren-Lawrence grades. Kellgren-Lawrence grades were positively correlated with miR-145, TNF-α, and IL-6 (P < 0.05), and negatively correlated with IL-10 (P < 0.05). TNF: Tumor necrosis factor; IL: Interleukin.

Figure 7 Receiver operating characteristic curve analysis of miR-145 and inflammatory factors in differentiating Kellgren-Lawrence grades.