Impact of an acute hemodynamic response-guided protocol for primary prophylaxis of variceal bleeding

Figure 1 Flowchart of the study selection process. HVPG: Hepatic venous pressure gradient; NSBB: Nonselective beta-blockers.

Figure 2 Correlation between acute and chronic changes in HVPG in the traditional nonselective beta-blockers group. Among 52 patients, 27 had a second hemodynamic study after 26.3 ± 12.8 wk. HVPG: Hepatic venous pressure gradient.

Figure 3 Cumulative probability of decompensation in patients with previously compensated liver disease (A) and patients with a history of hepatic decompensation (B). Patients with acute response receiving traditional NSBB are represented by a continuous line, and acute nonresponders receiving carvedilol are represented by a dashed line. P value corresponds to log-rank test at the end of follow-up. NSBB: Nonselective beta-blockers.

Figure 4 Cumulative probability of transplant-free survival in patients with previously compensated liver disease (A) and patients with a history of hepatic decompensation (B). Patients with acute response receiving traditional NSBB are represented by a continuous line, and acute nonresponders receiving carvedilol are represented by a dashed line. P value corresponds to log-rank test at the end of follow-up. NSBB: Nonselective beta-blockers.