Case Report
Copyright ©The Author(s) 2025.
World J Clin Cases. Mar 26, 2025; 13(9): 99964
Published online Mar 26, 2025. doi: 10.12998/wjcc.v13.i9.99964
Figure 1
Figure 1 The magnetic resonance examination results consider the high possibility of bone giant cell tumor. A and B: A solid mass located entirely in the left scapula, which showed a mass-like lesion with long T1 (A) and T2 (B) signals; orange arrow: Partially high signal on diffusion-weighted imaging sequence, unclear boundary with surrounding soft tissue, and uneven enhancement on enhanced scan. The left shoulder joint is in place, and there is a cystic proton density-weighted images high signal in the left humeral head; C and D: Regular imaging examinations were performed one year after treatment, orange arrow: The display signal of the lateral azimuth angle is weakened.
Figure 2
Figure 2 Based on histopathological examination, there was a preliminary suspicion of a tumor of epithelial origin, with the possibility of metastatic adenocarcinoma. A: The tumor cells presented diffuse infiltrative growth and a variety of morphological arrangements, including nested sheets and alveolar and tubular structures (hematoxylin and eosin × 40), black arrows point to tumor cells in various morphological arrangements; B: It presented as groups of solid cytoplasmic cells containing granules that resembled those found in serous acinar cells, which were clearly acinus (black arrow) in acinic cell carcinoma (hematoxylin and eosin × 400).
Figure 3
Figure 3 Immunophenotype of this case. A: Tumor cells were positive for CK pan (× 40); B: Tumor cells were positive for epithelial membrane antigen (× 40); C: Tumor cells were positive for S-100 (× 40); D: Tumor cells nucleus were positive for SOX-10 (× 40); E: Tumor cells were positive in 10% cells for Ki-67 (× 40); F: Tumor cells expressed cell margin membrane DOG-1 (× 40).