Hereditary alpha tryptasemia and clinical implications

Figure 1 Approach in venom anaphylaxis. HAT: Hereditary alpha tryptasemia; c-KIT: Tyrosine kinase protein; sBT: Serum basal tryptase.

Figure 2 Relationship. The relationship between hereditary alpha tryptasemia (HAT), systemic mastocytosis (SM), hymenoptera venom anaphylaxis (HVA) and mast cell activation syndrome (MCAS). A: The relationship between HAT, SM, and HVA; B: Relationship between HAT and MCAS. HAT: Hereditary alpha tryptasemia; HVA: Hymenoptera venom anaphylaxis; MCAS: Mast cell activation syndrome; MMAS: Monoclonal mast cell activation syndrome; SM: Systemic mastocytosis; CM: Cutaneous mastocytosis.

Figure 3 Clinical and laboratory approach to elevated serum basal tryptase. CBC: Complete blood count; GFR: Glomerular filtration rate; KIT: Tyrosine kinase protein; SBT: Serum basal tryptase; HAT: Hereditary alpha tryptasemia.