Primary mucosa associated lymphoid tissue lymphoma of the gallbladder: A case report and review of literature

Figure 1 Magnetic resonance imaging of gallbladder. Prostate magnetic resonance imaging depicted the gallbladder wall thickening (10 mm) with a low-intensity relative to the liver parenchyma on the T1-weighted.

Figure 2 Macroscopic image of gallbladder. The gallbladder wall appeared to be broadly thickened by approximately 1 cm.

Figure 3 Histologic findings of mucosa associated lymphoid tissue lymphoma of the gallbladder. A: Lymphoid tumor cells infiltrate whole layers of the gallbladder wall; B-C: Tumor cells infiltrate around the gallbladder mucosa (B) and liver parenchyma (C); D: Diffusely infiltrating tumor cells are small sized with inconspicuous nucleoli; E: Tumor cells infiltrate between cytokeratin-positive gallbladder mucosa, but do not form a lymphoepithelial lesion; F-H: Tumor cells are positive for CD20 (F), BCL2 (G), and Kappa light chain (H); I-P: Tumor cells are negative for TdT (I), CD3 (J), CD5 (K), CD10 (L), BCL6 (M), CD23 (N), cyclin D1 (O), and Lambda light chain (P). Original magnification: A: × 40; B-P: × 400.

Figure 4 Abdomen contrast-enhanced computed tomography imaging. A: Thickened gallbladder wall (10 mm) was observed with homogeneous enhancement shown on the arterial; B: Thickened gallbladder wall (10 mm) was observed with homogeneous enhancement shown on the portal; C: Thickened gallbladder wall (10 mm) was observed with homogeneous enhancement shown on the delayed phases. Also, contrast-enhanced computed tomography showed laminar enhancement on the liver bed, which indicated invasion of the hepatic bed.