Serum activin A as a prognostic biomarker for community acquired pneumonia

Figure 1 Serum levels of activin A in enrolled individuals. A: Serum activin A level distribution in different multiple groups and healthy volunteers, ^aP < 0.05; B: Serum activin A level distribution in different causative etiologies of community-acquired pneumonia in the study patients.

Figure 2 Correlation between serum activin A levels and biomarkers in different groups of community-acquired pneumonia. A: Positive correlation between activin A and CURB-65 scores in patients; B: Positive correlation between activin A and Pneumonia Severity Index scores in patients.

Figure 3 Receiver operating curve analysis for serum activin A concentrations to predict hospital mortality. A: Area under the receiver operating curve [areas under the curve (AUC)] for the biomarkers evaluated in this study; B: AUC of combination of activin A and CURB-65 or CURB-65 alone, P = 0.0005; C: AUC of combination of activin A and Pneumonia Severity Index (PSI) or PSI alone, P = 0.0094.