Diagnosis and management of benign recurrent intrahepatic cholestasis and psychosocial stressors in an adolescent: A case report

Figure 1 Histological images from the liver biopsy. A: Severe cholestasis in the centrilobular area without obvious inflammatory and fibrotic findings (H&E, 40×); B: Intrahepatocyte bile pigment with intact small bile duct in the portal area (H&E, 100×); C: Immunohistochemical staining for CD10, a cell surface enzyme present in normal bile ducts (100×). H&E: Hematoxylin and eosin.

Figure 2 Sequencing results of the ATP8B1 mutation. First-generation sequencing was taken and the results showed that the father was wild type and the patient had a mutation of c.1587_1589delCTT. The result of the first-generation sequencing was the reverse complementary sequence of the tested one and showed deletion of AAG.