Complex heterozygous mutations in hereditary spherocytosis: A case report

Figure 1 Sequencing results. A: ANK1 detected a new mutation from the patient's father; B: SPTA1 detected a new mutation from the patient's mother; C: The patient's sister ANK1 was not detected abnormal; D: Patient's sisters SPTA1 detected the genetic mutation of the mother.

Figure 2 Genealogy diagram.

Figure 3 Three-dimensional structure diagram of ANK1 protein. A: Wild type; B: After the mutation; amino acid site changes are indicated by arrows.