Systemic lupus erythematosus in a 15-year-old female with multiple splenic nodules: A case report

Figure 1 Abdominopelvic computed tomography images of the patient. A and B: Multiple low-density nodules up to 4 cm in the spleen.

Figure 2 Positron emission tomography-computed tomography images of the patient. A: Multiple hypermetabolic lymph nodes of various sizes along the left supraclavicular lymph node (SULmax, 3.6); B: Right axillary lymph node (SULmax, 2.7); C: Uneven hypermetabolic activities (SULmax, 3.1) observed in the spleen.

Figure 3 Histopathological findings of the lymph node. A: Lymph node biopsy reveals extensive subcapsular necrosis with hematoxylin bodies (hematoxylin and eosin stain, × 200); B: Higher magnification shows abundant crescentic histiocytes, abundant karyorrhectic debris, and small hematoxylin bodies (hematoxylin and eosin stain, × 400).

Figure 4 Gross findings after laparoscopic splenectomy. A and B: Multiple nodules observed on the surface of the spleen. No other specific findings were noted.

Figure 5 Histological findings of the spleen. A: Extensive periarteriolar necrosis with hematoxylin bodies (hematoxylin and eosin stain, × 100); B: Higher magnification of hematoxylin bodies and abundant karyorrhectic debris (hematoxylin and eosin stain, × 400).