Human immunodeficiency virus-associated dementia complex with positive 14-3-3 protein in cerebrospinal fluid: A case report

Figure 1 The 14–3–3 protein was found in cerebrospinal fluid, and 129 M/M and 219 E/E genotype was further verified. The 14-3-3 protein was positive, and the protein gene test showed M/M type.

Figure 2 Pre- and post-treatment cranial imaging examinations of the patient. A-D: Neuroradiological presentation of this patient before treatment; The brain computed tomography reveals encephalatrophy and demyelination in the white matter (A); Axial T1-weighted brain magnetic resonance imaging (MRI) with pre-contrast shows mild encephalatrophy and demyelination around the bilateral cerebral ventricles (B); Axial T1-weighted brain MRI with post-contrast displays no enhancement of any lesions (C and D); E and F: Neuroradiological presentation of this patient after treatment; Axial T1-weighted brain MRI with pre-contrast illustrates slight encephalatrophy and the significantly improved demyelination in the white matter around the bilateral cerebral ventricles (E); Axial T1-weighted brain MRI with post-contrast demonstrates no enhancement in any of the lesions (F).