Abemaciclib-induced lung damage leading to discontinuation in brain metastases from breast cancer: A case report

Figure 1 Initial head magnetic resonance imaging. The patient was diagnosed with multiple brain metastases based on contrast-enhanced head magnetic resonance imaging when she visited our hospital for the staggering that she began experiencing in the 11^th year postoperatively.

Figure 2 Magnetic resonance imaging before and after abemaciclib administration. A: Contrast-enhanced head magnetic resonance imaging (MRI) before abemaciclib plus letrozole treatment; B: Contrast-enhanced head MRI after abemaciclib plus letrozole treatment. The brain metastases shrunk, and the contrast effect was attenuated after treatment, almost reaching a partial response.

Figure 3 Computed tomography scan when diagnosing drug-induced lung disease. Computed tomography after abemaciclib plus letrozole treatment reveals a pale interstitial shadow on the right lung, which led to the diagnosis of drug-induced lung disease.