Adult localized Langerhans cell histiocytosis: A case report

Figure 1 Clinical feature. A: Red erosive plaques and ulcers on the vulva; B: Red erosive plaques and ulcers on the perianal area; C: Lesions after 6 mo of oral prednisone 20 mg orally.

Figure 2 Hematoxylin and eosin staining. A: The histiocytoid cells in the superficial and middle dermis layer with mild nuclear atypia, with occasional eosinophils; B: The histiocytoid cells in the superficial and middle dermis layer with mild nuclear atypia (orange arrow), with occasional eosinophils (yellow arrow).

Figure 3 Immunohistochemistry. A: CD1 (+++); B: S100 (+++); C: Ki-67 (30%); D: CK (-); E: CD68 (20%+).