Creutzfeldt-Jakob disease presenting as Korsakoff syndrome caused by E196A mutation in PRNP gene: A case report

Figure 1 Diffusion-weighted imaging and positron emission tomography/computed tomography of brain. A: Hyperintense signals observed in bilateral occipital, parietal, temporal, and frontal lobes. Hyperintense signals in bilateral thalamus (white arrow markers); B: Decreased diffuse fluorodeoxyglucose metabolism seen on the right cerebral cortex.

Figure 2 PRNP sequencing outcome. Red circle marks the presence of a c.A587C base heterozygous change in the second exon of PRNP.