Two methods of lung biopsy for histological confirmation of acute fibrinous and organizing pneumonia: A case report

Figure 1 Chest imaging changes. A–C: Chest computed tomography (CT) at the local hospital suggesting multiple exudative opacities in both lungs; D–F: Chest CT on admission revealed patchy, diffuse alveolar opacities and consolidation with bilateral and peripheral distributions after 9 d of anti-infective treatment in the local hospital; G–I: Chest CT shows that the lung opacities have decreased significantly after 3 d of steroid treatment; J–L: Chest CT shows that the lung opacities have almost been entirely absorbed after 1 mo of steroid treatment.

Figure 2 Histological findings in the lung. A and B: Ultrasound-guided right lung puncture biopsy reveals intra-alveolar fibrin in the form of “fibrin balls” without the formation of hyaline membranes [Hematoxylin and eosin (HE): 20 ×, HE: 40 ×, respectively]; C and D: Transbronchial lung biopsy of the left lower lobe: fibrin balls are present in the alveolar cavities (HE: 20 ×, HE: 40 ×, respectively).