Successful treatment of Morbihan disease with total glucosides of paeony: A case report

Figure 1 Facial lesions of the patient with Morbihan disease. A: Non-pitting edema and erythema of the upper two-thirds of the face; B: The lesions disappeared completely after 4 mo of treatment with total glucosides of paeony capsules, and follow-up of almost 1 yr showed no recurrence.

Figure 2 Histopathology of the patient's facial skin lesions. A-C: Hyperkeratosis of the epidermis, nodular inflammatory lesions in the dermis, epithelioid granuloma, and inflammatory infiltrating cells dominated by lymphocytes and histiocytes around skin appendages and blood vessels (HE staining A: × 4; B: × 20; C: × 40); D: Negative for Alcian blue staining (× 20); E: Negative for acid fast staining (× 20); F: Negative for silver staining (× 20); G: Negative for periodic acid-Schiff staining (× 20).