Efficacy and safety of adalimumab in comparison to infliximab for Crohn's disease: A systematic review and meta-analysis

Figure 1 Flow chart for literature search. IFX: Infliximab; ADA: Adalimumab; CTZ: Certolizumab; CD: Crohn’s disease; UC: Ulcerative colitis.

Figure 2 Forest plot for induction efficacy comparing adalimumab and infliximab. A: Induction of response; B: Induction of remission. ADA: Adalimumab; IFX: Infliximab; CI: Confidence interval.

Figure 3 Forest plot for maintenance efficacy comparing adalimumab and infliximab. A: Maintenance of response; B: Maintenance of remission. ADA: Adalimumab; IFX: Infliximab; CI: Confidence interval.

Figure 4 Forest plot comparing infliximab and adalimumab for the incidence of secondary loss of response. ADA: Adalimumab; IFX: Infliximab; CI: Confidence interval.

Figure 5 Forest plot for comparisons of the rate of adverse events for adalimumab and infliximab. A: Overall adverse events; B: Severe adverse events; C: Opportunistic infection. ADA: Adalimumab; IFX: Infliximab; CI: Confidence interval.

Figure 6 Funnel plot. A: Maintenance of response; B: Maintenance of remission; C: Secondary loss of response; D: Overall adverse events. OR: Odds ratio; SE: Standard error.