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World J Clin Cases. Jan 7, 2022; 10(1): 12-22
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.12
Figure 1
Figure 1 Hepatitis B virus life cycle and mechanisms associated with hepatitis B virus reactivation linked to immunosuppressive therapies. APC: Antigen presenting cell; CTL cell: Cytotoxic T lymphocyte cell; cccDNA: Covalently closed circular DNA; IFN: Interferon; TNF-α: Tumour necrosis factor α; JAK: Janus kinase; HBV: Hepatitis B virus.
Figure 2
Figure 2 Suggested process for screening, monitoring, and prevention of hepatitis B virus reactivation. HBsAg: Hepatitis B surface antigen; anti-HBs: Antibody to hepatitis B surface antibody; anti-HBc: Antibody to hepatitis B core antigen; ISDs: Immunosuppressive drugs; CS: Corticosteroid; HBV: Hepatitis B virus.