Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2021; 9(34): 10430-10437
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10430
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10430
Association between celiac disease and vitiligo: A review of the literature
Jing-Zhan Zhang, Dilinuer Abudoureyimu, Shi-Rong Yu, Xiao-Jing Kang, Department of Dermatology, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research, Urumqi 830001, Xinjiang Uygur Autonomous Region, China
Man Wang, Department of Gastroenterology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang Uygur Autonomous Region, China
Author contributions: Zhang JZ designed the study and drafted the article; Abudoureyimu D, Wang M, Yu SR and Kang XJ revised the article critically for important intellectual content; all the authors approved the version to be published.
Supported by National Natural Science Foundation of China , No. 81760563 .
Conflict-of-interest statement: All authors declare no conflicts-of-interest related to this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Jing Kang, MD, PhD, Chairman, Chief Doctor, Professor, Department of Dermatology, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research, NO. 91 Tianchi Road, Tianshan District, Urumqi 830001, Xinjiang Uygur Autonomous Region, China. drkxj@sina.com
Received: May 2, 2021
Peer-review started: May 2, 2021
First decision: June 12, 2021
Revised: June 25, 2021
Accepted: October 20, 2021
Article in press: October 20, 2021
Published online: December 6, 2021
Peer-review started: May 2, 2021
First decision: June 12, 2021
Revised: June 25, 2021
Accepted: October 20, 2021
Article in press: October 20, 2021
Published online: December 6, 2021
Core Tip
Core Tip: Both celiac disease (CD) and vitiligo are autoimmune-related diseases, and their global incidence rates are similar (approximately 1%). This article reviews recent studies on the relationship between CD and vitiligo, and gluten-free diet (GFD) and vitiligo and explores their possible pathogenesis. An analysis based on existing evidence supports the association between CD and vitiligo. Patients with vitiligo and positive serum gluten markers, or with CD, may benefit from a GFD; it could be a valid option depending on the patient's preference. We hope this review will be useful for future treatment.