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Sato R, Kakinuma S, Mochizuki S, Uchiyama A, Meguro S, Matsumoto R. A Rare Case of Spermatic Cord Metastasis Following Surgery for Transverse Colon Cancer. Cureus 2025; 17:e80679. [PMID: 40236342 PMCID: PMC11999739 DOI: 10.7759/cureus.80679] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 03/16/2025] [Indexed: 04/17/2025] Open
Abstract
We report a rare case of spermatic cord (SC) metastasis in a 44-year-old man with a history of transverse colon cancer. He had undergone laparoscopic right hemicolectomy followed by adjuvant chemotherapy and remained under routine follow-ups with no signs of recurrence. He presented with painless right scrotal swelling, and imaging revealed an SC tumor (SCT). Serum tumor markers were within the normal ranges. Radical orchiectomy was performed, and histopathology confirmed metastatic adenocarcinoma from the transverse colon. Local recurrence was detected four months postoperatively, and the patient is currently receiving multidisciplinary treatment. Metastatic SCTs, although rare, need to be considered in patients with a history of gastrointestinal cancer, even without elevated tumor markers.
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Affiliation(s)
- Ryo Sato
- Department of Urology, Chutoen General Medical Center, Kakegawa, JPN
- Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, JPN
| | - Shungo Kakinuma
- Department of Urology, Chutoen General Medical Center, Kakegawa, JPN
- Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, JPN
| | | | - Asuka Uchiyama
- Department of Urology, Chutoen General Medical Center, Kakegawa, JPN
- Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, JPN
| | - Shiori Meguro
- Department of Regenerative and Infectious Pathology, Hamamatsu University School of Medicine, Hamamatsu, JPN
| | - Rikiya Matsumoto
- Department of Urology, Chutoen General Medical Center, Kakegawa, JPN
- Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, JPN
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2
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Gabriel H, Hammond NA, Marquez RA, Lopes Vendrami C, Horowitz JM, Casalino DD, Nikolaidis P, Miller FH, Bhatt S. Gamut of Extratesticular Scrotal Masses: Anatomic Approach to Sonographic Differential Diagnosis. Radiographics 2023; 43:e220113. [PMID: 36893051 DOI: 10.1148/rg.220113] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 03/10/2023]
Abstract
The commonly taught tenet that intratesticular lesions are always malignant and extratesticular scrotal lesions are always benign is a simplistic statement that erroneously minimizes the significance of extratesticular scrotal masses and their diagnosis. Yet, disease in the extratesticular space is commonly encountered by clinicians and radiologists and is often a source of uncertainty in diagnosis and management. Given the embryologically rooted complex anatomy of this region, a wide range of pathologic conditions is possible. Radiologists may not be familiar with some of these conditions; further, many of these lesions can have a specific sonographic appearance, allowing accurate diagnosis that can minimize surgical intervention. Lastly, malignancies can occur in the extratesticular space-although this is less common than in the testicles-and proper recognition of findings that warrant additional imaging or surgery is critical in optimizing outcomes. The authors present a compartmental anatomic framework for differential diagnosis of extratesticular scrotal masses and provide a comprehensive illustrative display of many of the pathologic conditions that can be encountered to familiarize radiologists with the sonographic appearances of these lesions. They also review management of these lesions and scenarios where US may not be definitive in diagnosis and selective use of scrotal MRI can be helpful. © RSNA, 2023 Quiz questions for this article are available in the supplemental material.
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Affiliation(s)
- Helena Gabriel
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Nancy A Hammond
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Rocio A Marquez
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Camila Lopes Vendrami
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Jeanne M Horowitz
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - David D Casalino
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Paul Nikolaidis
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Frank H Miller
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
| | - Shweta Bhatt
- From the Department of Radiology, Northwestern University, 676 N St. Clair St, Suite 800, Chicago, IL 60611 (H.G., N.A.H., R.A.M., C.L.V., J.M.H., D.D.C., P.N., F.H.M.); and Department of Radiology, Mayo Clinic, Jacksonville, Fla (S.B.)
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Suto H, Inui Y, Okamura A. Case report: Paratesticular dedifferentiated liposarcoma with poor prognosis. Front Oncol 2022; 12:1085794. [PMID: 36531026 PMCID: PMC9754323 DOI: 10.3389/fonc.2022.1085794] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/31/2022] [Accepted: 11/15/2022] [Indexed: 08/29/2023] Open
Abstract
BACKGROUND/AIM Most paratesticular liposarcomas (PLPSs) are well-differentiated liposarcomas (WDLPSs) with favourable prognoses. As such, the rare occurrence of PLPS often leads to its misdiagnosis as a hernia or hydrocele on physical examination. Curative resection of the tumour may not be possible in cases where PLPSs have transformed into dedifferentiated liposarcomas (DDLPSs) owing to a delay in diagnosis. Herein, we describe a case of unresectable paratesticular dedifferentiated liposarcoma (PDDLPS) with poor prognosis due to delayed diagnosis. CASE REPORT A 57-year-old man visited our hospital with a chief complaint of a right scrotal mass, which was diagnosed as scrotal hydrocele but without treatment or follow-up. Eight years later, the patient complained of abdominal distension, and a computed tomography scan revealed the presence of retroperitoneal and right scrotal masses. The right scrotal mass was removed, and histopathology revealed DDLPS. The patient was diagnosed with unresectable PDDLPS metastasising to the retroperitoneum, and the left pleura was treated with doxorubicin. After an initial response, pleural effusion and ascites increased during the sixth cycle of chemotherapy. The patient subsequently received eribulin but died 5 months after the initial DDLPS diagnosis. CONCLUSION It is difficult to distinguish PLPS from benign inguinal hernia and hydrocele testis on physical examination. PLPS generally has a considerably good prognosis. However, failure to diagnose WDLPS can be dangerous as it might lead to malignant transformation to DDLPS, which has a poor prognosis. Physicians should consider this malignancy when examining patients with hernias or hydroceles of the inguinal region and should perform ultrasonography or magnetic resonance imaging.
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Affiliation(s)
- Hirotaka Suto
- Department of Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan
- Department of Medical Oncology/Haematology, Kakogawa Central City Hospital, Hyogo, Japan
| | - Yumiko Inui
- Department of Medical Oncology/Haematology, Kakogawa Central City Hospital, Hyogo, Japan
| | - Atsuo Okamura
- Department of Medical Oncology/Haematology, Kakogawa Central City Hospital, Hyogo, Japan
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Fu J, Luo J, Ye H, Chen Y, Xie L. Testicular and Spermatic Cord Metastases from Gastric Adenocarcinoma: An Unusual Case. Cancer Manag Res 2021; 13:1897-1900. [PMID: 33654434 PMCID: PMC7914050 DOI: 10.2147/cmar.s286909] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/15/2020] [Accepted: 01/29/2021] [Indexed: 12/22/2022] Open
Abstract
The metastasis of gastric cancer to the testis or spermatic cord is very rare; however, simultaneous testicular and spermatic cord metastases are even rarer. Here, we report an unusual case of a 54-year-old male patient who had undergone radical gastrectomy for gastric adenocarcinoma more than two years before. He complained of palpable painful masses in the right scrotum and inguinal area occurring for more than half a year. Enhanced computed tomography (CT) separately showed an enhanced soft tissue mass in the right testicular and spermatic cord areas. Therefore, a right radical orchiectomy was conducted. The pathology was consistent with the metastases of gastric adenocarcinoma.
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Affiliation(s)
- Jing Fu
- Department of Urology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, People's Republic of China.,Department of Urology, Shaoxing Second Hospital, Shaoxing, Zhejiang, 312000, People's Republic of China
| | - Jindan Luo
- Department of Urology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, People's Republic of China
| | - Huajian Ye
- Department of Urology, Shaoxing Second Hospital, Shaoxing, Zhejiang, 312000, People's Republic of China
| | - Yaokang Chen
- Department of Urology, Shaoxing Second Hospital, Shaoxing, Zhejiang, 312000, People's Republic of China
| | - Liping Xie
- Department of Urology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, People's Republic of China
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Tsao SH, Chuang CK. Krukenberg tumor with concomitant ipsilateral hydronephrosis and spermatic cord metastasis in a man: A case report. World J Clin Cases 2021; 9:278-283. [PMID: 33511197 PMCID: PMC7809680 DOI: 10.12998/wjcc.v9.i1.278] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/07/2020] [Revised: 11/03/2020] [Accepted: 11/12/2020] [Indexed: 02/06/2023] Open
Abstract
BACKGROUND Tumors of the spermatic cord are rare, and approximately 25% are malignant neoplasms. Metastatic spermatic cord tumors are even rarer. Several studies have revealed that the most frequent primary tumors metastasizing to the spermatic cord and peritesticular tissues are neoplasms of the stomach and prostate. Furthermore, metastasis to the spermatic cord or epididymis may occur via retrograde lymphatic and hematic routes. We present the case of a man with gastric cancer that metastasized to the spermatic cord and epididymis, with concomitant ipsilateral hydronephrosis after surgical resection and chemotherapy for his primary tumor.
CASE SUMMARY A 71-year-old man underwent total gastrectomy for pT4aN2 poorly differentiated gastric adenocarcinoma in December 2016. Two months after surgery, he received adjuvant chemotherapy with TS-1 from February 2017 to February 2018. Surveillance computed tomography (CT) was performed in June 2018, which did not reveal any sign of tumor recurrence. In November 2019, he presented with left lower quadrant abdominal pain and a palpable left inguinal-scrotal mass. CT revealed left mild hydronephrosis and a left scrotal mass measuring 4.0 cm × 1.7 cm. Tumor biomarkers, including alpha-fetoprotein (AFP), lactate dehydrogenase (LDH), beta-human chorionic gonadotropin (βHCG), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) were all normal. Renal and testicular echography showed left hydronephrosis and a left peritesticular soft tissue lesion with blood flow. Diagnostic ureteroscopy showed left lower ureter narrowing without an intraluminal lesion. A biopsy was obtained for the indurated spermatic cord and epididymis, which showed poorly differentiated adenocarcinoma. Immunohistochemical staining demonstrated that the tumor was diffusely and strongly positive for homeobox protein CDX2. The features were consistent with metastatic adenocarcinoma of a primary gastric tumor.
CONCLUSION In patients with a history of primary cancer, an inguinal mass of unknown cause with accompanying ipsilateral hydronephrosis may be a sign of distant metastasis from a primary tumor, especially of gastrointestinal origin.
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Affiliation(s)
- Shu-Han Tsao
- Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Taoyuan City 333, Taiwan
| | - Cheng-Keng Chuang
- Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Taoyuan City 333, Taiwan
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Ramanathan S, Palaniappan Y, Sheikh A, Ryan J, Kielar A. Crossing the canal: Looking beyond hernias — Spectrum of common, uncommon and atypical pathologies in the inguinal canal. Clin Imaging 2017; 42:7-18. [DOI: 10.1016/j.clinimag.2016.11.004] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/16/2016] [Revised: 10/25/2016] [Accepted: 11/04/2016] [Indexed: 01/09/2023]
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Matsutani T, Nomura T, Hagiwara N, Fujita I, Kanazawa Y, Kakinuma D, Kanno H, Matsuda A, Uchida E. Laparoscopic Diagnosis for Spermatic Cord Metastasis from Esophageal Squamous Cell Carcinoma: Report of a Case. J NIPPON MED SCH 2016; 82:304-7. [PMID: 26823036 DOI: 10.1272/jnms.82.304] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/19/2022]
Abstract
We report a case of previously unreported metastasis to the spermatic cord from esophageal squamous cell carcinoma. A 63-year-old Japanese man underwent laparoscopy-assisted esophageal bypass surgery for an advanced esophageal cancer. An elastic hard tumor was found in the right lateral inguinal fossa on intraoperative laparoscopy, and laparoscopic enucleation was performed. Histological examination of the resected tumor revealed a moderately differentiated squamous cell carcinoma, compatible with metastasis from the esophageal cancer. Two months after the operation, computed tomography revealed a heterogeneously enhanced groin mass (20 mm in diameter) involving the right spermatic cord. To our knowledge, this is the first reported case of a solitary metastasis to the spermatic cord from esophageal squamous cell carcinoma.
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Affiliation(s)
- Takeshi Matsutani
- Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School
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Metastatic Tumor of the Spermatic Cord in Adults: A Case Report and Review. Case Rep Urol 2015; 2015:747261. [PMID: 26770863 PMCID: PMC4681788 DOI: 10.1155/2015/747261] [Citation(s) in RCA: 5] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/27/2015] [Accepted: 11/18/2015] [Indexed: 02/07/2023] Open
Abstract
Metastatic spermatic cord (SC) tumor is extremely rare. Recently, we experienced a case of late-onset metastatic SC tumor from cecal cancer. This case is a 68-year-old man presenting with a painless right SC mass. He had undergone a right hemicolectomy for cecal cancer 6 years ago. Radical orchiectomy and adjuvant chemotherapy with S-1 were performed. No recurrence was found after one year of follow-up. We identified a total of 25 cases, including our case, on a literature search via PubMed from January 2000 to April 2015. The most frequent primary sites of the tumors metastasizing to the SC were the stomach (8 cases, 32%) and the colon (8 cases, 32%), next the liver (2 cases, 8%), and kidney (2 cases, 8%). The majority of the cases underwent radical orchiectomy for the metastatic tumors of the SC. Over half of the cases received adjuvant interventions based on the regimens for the primary tumors. Prognosis in the patients with metastatic tumor of the SC was unfavorable except for late-onset metastasis. In patients with a mass in the SC and a history of neoplasm, especially in gastrointestinal tract, the possibility of metastasis from the primary cancer should be considered.
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9
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Jang JG, Jeong HY, Kim KS, Park MJ, Lee JS, Kim SS, Kim HY. Metastatic Spermatic Cord Tumor From Colorectal Cancer. Ann Coloproctol 2015; 31:202-4. [PMID: 26576400 PMCID: PMC4644709 DOI: 10.3393/ac.2015.31.5.202] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 06/10/2015] [Accepted: 08/18/2015] [Indexed: 12/03/2022] Open
Abstract
Metastatic tumors of the spermatic cord are extremely rare, and the prognosis for patients is typically poor. In the majority of cases, the primary tumor occurs in the gastrointestinal tract. We report a case of a 62-year-old man with a metastatic spermatic cord tumor. The patient complained of groin discomfort with a tender mass in the right inguinal area. An excisional biopsy was performed, and the pathologic finding was a metastatic mucinous adenocarcinoma. We performed a systemic evaluation including colonoscopy, abdominal computed tomography, and total-body positron emission tomography, and the primary tumor was confirmed to involve the total colon, including the cecum, sigmoid colon, and rectum. The pathologic finding for rectum revealed a mucinous adenocarcinoma compatible with a metastatic spermatic cord tumor.
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Affiliation(s)
- Ji Geon Jang
- Department of Internal Medicine, Good Samsun Hospital, Busan, Korea
| | - Hye Yun Jeong
- Department of Internal Medicine, Good Samsun Hospital, Busan, Korea
| | - Ki Soo Kim
- Department of Internal Medicine, Good Samsun Hospital, Busan, Korea
| | - Mi Jung Park
- Department of Internal Medicine, Good Samsun Hospital, Busan, Korea
| | - Jin Sook Lee
- Department of Pathology, Good Samsun Hospital, Busan, Korea
| | - Sang Su Kim
- Department of Radiology, Good Samsun Hospital, Busan, Korea
| | - Ho Young Kim
- Department of Surgery, Good Samsun Hospital, Busan, Korea
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10
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Spermatic cord metastasis of gastric cancer diagnosed from right groin pain. Int Cancer Conf J 2015. [DOI: 10.1007/s13691-014-0190-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/24/2022] Open
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11
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Thomas R, Swamy S. Rare case of gastrointestinal stromal tumor presenting with scrotal metastasis. Indian J Surg 2015; 77:188-9. [PMID: 25972692 DOI: 10.1007/s12262-015-1260-5] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/06/2014] [Accepted: 03/09/2015] [Indexed: 11/25/2022] Open
Abstract
While gastrointestinal stromal tumors frequently metastasize, the scrotum is an extremely rare site of involvement. This case is of a 48-year-old male who, having undergone debulking surgery for metastatic gastrointestinal stromal tumor (GIST) of the small intestine 2 years ago, presented with bilateral scrotal swelling. Ultrasound showed hypoechoic mass lesions surrounding the testis and epididymis bilaterally with extension into the spermatic cord and biopsy established a diagnosis of metastatic GIST of the scrotum. As the processus vaginalis is an extension of the peritoneal cavity, we postulate that it may serve a route of spread in malignancies that involve the peritoneal cavity, as in this case.
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Affiliation(s)
- Richard Thomas
- Department of Radiology, St. John's Medical College Hospital, Sarjapur Road, Bangalore, Karnataka 560034 India
| | - Smrita Swamy
- Department of Radiology, St. John's Medical College Hospital, Sarjapur Road, Bangalore, Karnataka 560034 India
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12
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Kim JH, Kim DS, Cho HD, Lee MS. Late-onset metastatic adenocarcinoma of the spermatic cord from primary gastric cancer. World J Surg Oncol 2014; 12:128. [PMID: 24767516 PMCID: PMC4026119 DOI: 10.1186/1477-7819-12-128] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/10/2013] [Accepted: 04/15/2014] [Indexed: 01/08/2023] Open
Abstract
BACKGROUND Metastatic cancers of the paratesticular tissue are very rare; however, the most frequent primary site of spermatic cord metastasis is the gastrointestinal tract. CASE PRESENTATION We recently observed two cases of late-onset metastatic adenocarcinoma of the spermatic cord. Both patients complained of groin discomfort with a palpable mass in the scrotum and inguinal area. Radical orchiectomy and adjuvant chemotherapy were performed in both patients. Although the prognosis of patients with metastatic adenocarcinoma of the spermatic cord is typically poor, the prognosis of our patients was favorable after follow-up for 14 to 18 months. CONCLUSIONS In patients with groin discomfort or swelling and a history of gastric cancer, metastatic adenocarcinoma should be included in the differential diagnosis for early detection of tumors.
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Affiliation(s)
| | - Doo Sang Kim
- Department of Urology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, 23-20, Bongmyeongdong, Cheonan, Chungnam 330-721, Korea.
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13
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Kim YW, Kim JW, Kim JH, Lee J, Lee E, Kim MY, Yang HK, Chang H. Metastatic testicular tumor presenting as a scrotal hydrocele: An initial manifestation of pancreatic adenocarcinoma. Oncol Lett 2014; 7:1793-1795. [PMID: 24932235 PMCID: PMC4049672 DOI: 10.3892/ol.2014.2009] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/18/2013] [Accepted: 02/20/2014] [Indexed: 12/25/2022] Open
Abstract
Metastatic pancreatic adenocarcinoma involving the testis is a rare condition with a poor prognosis. The current study describes the case of a 69-year-old male who presented with a painful swelling of the left scrotum. Scrotal ultrasonography revealed hydroceles in the scrotal sacs, with the left one being larger in size. The patient underwent left hydrocelectomy and was eventually diagnosed with metastatic adenocarcinoma. Abdominal computed tomography, which was performed to detect the primary cancer, showed a pancreatic tail carcinoma with liver and multiple lymph node metastases, and peritoneal carcinomatosis. The patient received gemcitabine-based chemotherapy but resulted in progressive disease. This case shows that in a patient in whom a primary testicular tumor is unusual due to their age, a testicular mass or hydrocele should be a suspect for possible metastatic disease.
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Affiliation(s)
- Yeon Wook Kim
- Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea
| | - Jin Won Kim
- Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
| | - Jee-Hyun Kim
- Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
| | - Jungsil Lee
- Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea
| | - Euijae Lee
- Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea
| | - Moon Young Kim
- Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea
| | - Hyun Kyung Yang
- Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
| | - Hyun Chang
- Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
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14
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Seike M, Kanazawa Y, Ohashi R, Machida T, Suzuki Y, Aimoto T, Kubota K, Gemma A. Metastatic mechanism of spermatic cord tumor from stomach cancer. Int Cancer Conf J 2013. [DOI: 10.1007/s13691-013-0123-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/26/2022] Open
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15
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Valizadeh N, Oskuie AE, Tehranchi A. Spermatic cord metastasis as early manifestation of small bowel adenocarcinoma. Urol Ann 2013; 5:53-5. [PMID: 23662014 PMCID: PMC3643327 DOI: 10.4103/0974-7796.106971] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/11/2011] [Accepted: 06/18/2011] [Indexed: 12/26/2022] Open
Abstract
Malignant tumors of the spermatic cord are rare. There are a few case reports on spermatic cord metastasis from colonic, gastric, pancreas, and prostatic cancer. Here, we report a 36-year-old man with brucellosis presenting with spermatic cord metastasis as early manifestation of small bowel adenocarcinoma.
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Affiliation(s)
- Nasim Valizadeh
- Assistant Professor of Hematology/Medical Oncology, Urmia University of Medical Sciences, Urmia, Iran
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16
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Lee KY, Park SJ, Moon SK, Kim HC. Unilateral spermatic cord metastasis from gastric cancer: a case report. IRANIAN JOURNAL OF RADIOLOGY 2012; 9:217-9. [PMID: 23408129 PMCID: PMC3569555 DOI: 10.5812/iranjradiol.8519] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 03/09/2011] [Revised: 07/16/2012] [Accepted: 07/28/2012] [Indexed: 11/29/2022]
Abstract
Malignant spermatic cord tumor is rare. Spermatic cord metastasis is less common and the prognosis of these patients is poor. Here we report a case of unilateral spermatic cord metastasis from advanced gastric cancer. A 57-year-old male underwent total gastrectomy due to advanced gastric cancer. Three years later, a painless hard palpable mass in the left inguinal area developed and the pathology revealed a spermatic cord metastasis from stomach cancer.
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Affiliation(s)
- Kang Young Lee
- Department of Radiology, Soonchunhyang University Hospital, Hoegi-dong, Republic of Korea
| | - Seong Jin Park
- Department of Diagnostic Radiology, Kyung Hee University Hospital, Hoegi-dong, Republic of Korea
- Corresponding author: Seong Jin Park, Department of Diagnostic Radiology, Kyung Hee University Hospital, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Hoegi-dong, Republic of Korea. Tel.: + 082-29588610, Fax: +082-29680787, E-mail:
| | - Sung Kyoung Moon
- Department of Diagnostic Radiology, Kyung Hee University Hospital, Hoegi-dong, Republic of Korea
| | - Hyun Cheol Kim
- Department of Radiology, Kyung Hee University Hospital, Sangil-dong, Gangdong, Republic of Korea
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Metastatic adenocarcinoma of the epididymis from pancreatic cancer successfully treated by chemotherapy and high-intensity focused ultrasound therapy: a case report and review of the literature. Pancreas 2011; 40:1160-2. [PMID: 21926538 DOI: 10.1097/mpa.0b013e318221816d] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/10/2022]
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18
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Correa JJ, Fishman M, Chuang ST, Spiess PE. Surgery plus targeted therapy for renal cell carcinoma with isolated spermatic cord metastasis. Clin Genitourin Cancer 2010; 7:E101-3. [PMID: 19815479 DOI: 10.3816/cgc.2009.n.034] [Citation(s) in RCA: 7] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/16/2023]
Abstract
We present a case of renal cell carcinoma with metastasis to the ipsilateral spermatic cord. We report the clinical presentation and management of this case and review the scientific literature of this unusual case presentation.
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Affiliation(s)
- Jose J Correa
- Department of Urologic Oncology and Genitourinary Medical Oncology, H. Lee Moffitt Cancer and Research Center, Tampa, FL 33612, USA
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19
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Abstract
The diverse embryological origins of the contents of the scrotum create an environment that fosters a wide variety of unusual pathologies. Most scrotal pathologies are discovered by the patient and are initially evaluated by a thorough physical examination and scrotal ultrasonography. Scrotal lesions can be broadly grouped by the anatomical location in which they develop; the clinician must consider a wide differential diagnosis based on this location. Solid testicular masses are considered germ cell tumors until proven otherwise, but numerous other possible pathologies exist, including ectopic tissue, metastasis, and other neoplastic growths. Rete testis lesions are classified as developmental, benign or malignant. Cystic lesions of the epididymis are most commonly benign, but malignant neoplasms can also be present. The paratesticular region has the broadest differential diagnosis, as it contains numerous distinct structures and is a common location for ectopic tissue and metastatic disease; a narrower range of lesions develop in the scrotal wall because of its simpler anatomy. Treatment options range from conservative observation to wide surgical excision and should be considered carefully; the aim of therapy is to remove malignant or potentially malignant tissue while minimizing effects on fertility and function.
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20
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Braun KP, Gastinger I, Theissig F, May M, Ernst H. [Rare tumor of the epididymis]. Internist (Berl) 2009; 50:1022-4. [PMID: 19436976 DOI: 10.1007/s00108-008-2296-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 10/20/2022]
Abstract
A 51-year-old man with known ethyl toxic chronic pancreatitis presented with a tumor of the left epididymis. Immunohistological examination disclosed it as a metastasis of a pancreatic carcinoma. Paratesticular metastases of a pancreatic carcinoma are very rare. Nevertheless a metastasis of a primary pancreatic carcinoma should be included in the differential diagnosis of a tumor of the paratesticular tissue. The epididymis should be integrated in the diagnostic procedures of pancreatic carcinoma.
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Affiliation(s)
- K-P Braun
- IV. Medizinische Klinik, Carl-Thiem-Klinikum, Breisacher Strasse 64, Cottbus, Germany.
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21
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Galanis I, Chatzimavroudis G, Katsougiannopoulos A, Galanis N, Makris J, Atmatzidis K. Spermatic cord metastasis presenting as strangulated inguinal hernia - first manifestation of a multifocal colon adenocarcinoma: a case report. CASES JOURNAL 2009; 2:61. [PMID: 19149893 PMCID: PMC2647912 DOI: 10.1186/1757-1626-2-61] [Citation(s) in RCA: 5] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 10/31/2008] [Accepted: 01/16/2009] [Indexed: 01/21/2023]
Abstract
Spermatic cord is a rare metastatic site of colorectal cancer. We herein report a case of spermatic cord metastasis of a previous undiagnosed multifocal colon adenocarcinoma, which was clinically presented as a strangulated groin hernia.
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Affiliation(s)
- Ioannis Galanis
- 2nd Surgical Department, Aristotle University of Thessaloniki, "G, Gennimatas" General Hospital, Thessaloniki, Greece.
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22
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Yeo JK. Scrotal Hydrocele as the First Clinical Manifestation of Occult Gastric Cancer. Korean J Urol 2009. [DOI: 10.4111/kju.2009.50.11.1151] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/18/2022] Open
Affiliation(s)
- Jeong Kyun Yeo
- Department of Urology, College of Medicine, Inje University, Pusan, Korea
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23
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Levy B, Lavelle M, Davies J, Rockall T. Testicular metastasis found in a patient with previous large bowel tumour. BMJ Case Rep 2009; 2009:bcr06.2008.0339. [PMID: 21686852 DOI: 10.1136/bcr.06.2008.0339] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/04/2022] Open
Abstract
Epididymo-testicular metastasis arising from a colonic primary neoplasm is exceptionally rare. We present two cases, one where the ipsilateral intrascrotal metastasis was evidence of recurrence 3 years after colonic surgery, and the other where the contralateral epididymo-testicular metastasis was the initial presentation.
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Affiliation(s)
- Bruce Levy
- MATTU, Daphne Jackson Road, Guildford, GU2 7WG, UK
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24
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Bhosale PR, Patnana M, Viswanathan C, Szklaruk J. The inguinal canal: anatomy and imaging features of common and uncommon masses. Radiographics 2008; 28:819-35; quiz 913. [PMID: 18480486 DOI: 10.1148/rg.283075110] [Citation(s) in RCA: 86] [Impact Index Per Article: 5.1] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/22/2023]
Abstract
A variety of benign and malignant masses can be found in the inguinal canal (IC). Benign causes of masses in the IC include spermatic cord lipoma, hematoma, abscess, neurofibroma, varicocele, desmoid tumor, air, bowel contrast material, hydrocele, and prostheses. Primary neoplasms of the IC include liposarcoma, Burkitt lymphoma, testicular carcinoma, and sarcoma. Metastases to the IC can occur from alveolar rhabdomyosarcoma, monophasic sarcoma, prostate cancer, Wilms tumor, carcinoid tumor, melanoma, or pancreatic cancer. In patients with a known malignancy and peritoneal carcinomatosis, the diagnosis of metastases can be suggested when a mass is detected in the IC. When peritoneal disease is not evident, a mass in the IC is indicative of stage IV disease and may significantly alter clinical and surgical treatment of the patient. A combination of the clinical history, symptoms, laboratory values, and radiologic features aids the radiologist in accurately diagnosing mass lesions of the IC. Supplemental material available at radiographics.rsnajnls.org/cgi/content/full/28/3/819/DC1.
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Affiliation(s)
- Priya R Bhosale
- Department of Radiology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 368, Houston, TX 77030, USA.
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25
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Bennett VS, Bailey DM. Cholangiocarcinoma presenting as a solitary epididymal metastasis: a case report and review of the literature. Diagn Pathol 2007; 2:33. [PMID: 17760973 PMCID: PMC2000863 DOI: 10.1186/1746-1596-2-33] [Citation(s) in RCA: 13] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/24/2007] [Accepted: 08/30/2007] [Indexed: 01/19/2023] Open
Abstract
BACKGROUND Solid tumor metastasis to the epididymis is a rare occurrence and is mostly discovered incidentally at autopsy or after therapeutic orchidectomy for prostate cancer. Other primary carcinomas that have been demonstrated to metastasize to the paratesticular region include those originating in the stomach, kidney, ileum, and colon. CASE PRESENTATION A 72-year-old gentleman presented with a firm and tender mass involving the right epididymis. On examination, he was jaundiced. Computed tomography of the abdomen demonstrated an obstructive stricture of the extra-hepatic bile ducts, in keeping with a cholangiocarcinoma, through which a metal stent was endoscopically inserted for symptomatic relief.Subsequent right radical orchidectomy yielded a diffusely infiltrative adenocarcinoma obliterating the epididymis, extending into the rete testis, vas deferens and spermatic cord and showing widespread vascular and perineural invasion. Residual epididymal, rete, and testicular tubules showed no in situ neoplasia. Morphologically and immunohistochemically the features were in keeping with a metastasis from a primary cholangiocarcinoma. CONCLUSION Only two cases of bile duct carcinoma metastasising to the male genital tract have previously been reported in the literature, the testis being the main site of metastasis in both cases. To our knowledge, this is the first described case of cholangiocarcinoma metastasising primarily to the epididymis, and presenting as a solitary epididymal metastasis in the absence of disseminated disease. It serves to highlight the importance of performing a thorough examination of the male external genitalia both clinically, in the follow up of cancer patients, and at autopsy.
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Affiliation(s)
- Victoria S Bennett
- Department of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK
| | - David M Bailey
- Department of Cellular Pathology, Wycombe General Hospital, Queen Alexandra Road, High Wycombe, Buckinghamshire, HP11 2TT, UK
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26
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Lee J, Kang SC, Ban JH, Shin DS, Yeo JK, Yoon DH, Moon DG, Yoon DK. Metastatic Tumor of Tunica Vaginalis Testis with Hydrocele in a Patient with Gastric Cancer. Korean J Urol 2007. [DOI: 10.4111/kju.2007.48.6.667] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/18/2022] Open
Affiliation(s)
- Jong Lee
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Seung Chul Kang
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Jung Hyun Ban
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Dong Shik Shin
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Jeong Kyun Yeo
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Dong Hee Yoon
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Du Geon Moon
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
| | - Duck Ki Yoon
- Department of Urology, College of Medicine, Korea University, Seoul, Korea
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27
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Kim HJ, Moon EJ, Kang WK, Hong SH, Jung CK, Oh ST. Sigmoid Colon Cancer with Metastasis to the Right Spermatic Cord. JOURNAL OF THE KOREAN SOCIETY OF COLOPROCTOLOGY 2007. [DOI: 10.3393/jksc.2007.23.3.203] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 10/21/2022]
Affiliation(s)
- Hyung Jin Kim
- Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea
| | - Eun Jung Moon
- Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea
| | - Won Kyung Kang
- Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea
| | - Seong Hu Hong
- Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea
| | - Chan Kwon Jung
- Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea
| | - Seong Taek Oh
- Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea
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28
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Seo IY, Kim SG, Han WC, Rim JS. Paratesticular mucinous cystadenocarcinoma: metastasis from pancreatic cancer. Int J Urol 2005; 11:1147-9. [PMID: 15663694 DOI: 10.1111/j.1442-2042.2004.00964.x] [Citation(s) in RCA: 14] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/29/2022]
Abstract
We experienced a case of a paratesticular mucinous adenocarcinoma from primary pancreatic cancer. A 67-year old man presented with a scrotal mass. Scrotal ultrasound showed a cystic mass on the testis. Radical orchiectomy was performed and the tumor was revealed as a mucinous cystadenocarcinoma separated from epididymis and testis. Metastatic cancer was suspected and abdominal computed tomography showed pancreatic cancer. We report this rare case of metastatic paratesticular cystoadenocarcinoma.
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Affiliation(s)
- Ill Young Seo
- Department of Urology, Wonkwang University School of Medicine, 344-2 Sinyong-dong, Iksan, Jeonbuk 570-180, Korea.
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29
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Amin MB. Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors. Mod Pathol 2005; 18 Suppl 2:S131-45. [PMID: 15502808 DOI: 10.1038/modpathol.3800314] [Citation(s) in RCA: 131] [Impact Index Per Article: 6.6] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/10/2022]
Abstract
The proximity and, in some instances, communication between several structures in the testis and paratestis (rete testis, epididymis, mesothelium, vestigial epithelium and paratesticular soft tissue) result in a plethora of interesting tumors and tumor-like lesions that together pose a formidable diagnostic challenge both because of their morphologic overlap and rarity. The occasional spread of tumors primarily at other sites to this region adds to the potential problem encountered. This review provides an overview of the pathology of nonmesenchymal paratesticular neoplasms and pseudotumors with a focus on the approach to tubulopapillary neoplasms for which diagnostic considerations may include carcinoma of the rete testis, malignant mesothelioma, ovarian-type epithelial tumors, epididymal carcinoma and metastatic carcinomas. The cornerstone of accurate characterization of these lesions is still a comprehensive, traditional clinicopathologic approach, clinical history (of another primary), gross examination (location) and routine light microscopy, but judicious incorporation of contemporary immunohistochemical markers may aid or in some instances be crucial in resolving the problems encountered.
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Affiliation(s)
- Mahul B Amin
- Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.
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30
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Amin MB. Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors. Mod Pathol 2005. [DOI: 10.1016/s0893-3952(22)04463-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/06/2023]
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31
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Mishra VC, Tindall SF. Case report--Prostatic carcinoma presenting as an epididymal nodule. Int Urol Nephrol 2002; 33:511. [PMID: 12230284 DOI: 10.1023/a:1019546718854] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.1] [Reference Citation Analysis] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/12/2022]
Affiliation(s)
- V C Mishra
- Department of Surgery, Scunthorpe General Hospital, UK.
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32
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Dutt N, Bates AW, Baithun SI. Secondary neoplasms of the male genital tract with different patterns of involvement in adults and children. Histopathology 2000; 37:323-31. [PMID: 11012739 DOI: 10.1046/j.1365-2559.2000.00983.x] [Citation(s) in RCA: 83] [Impact Index Per Article: 3.3] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/29/2022]
Abstract
AIMS The incidence, presentation and macroscopic and histological features of secondary neoplasms of the male genital tract are described with reference to their differential diagnosis. METHODS AND RESULTS A retrospective study of cases from the Royal London Hospital yielded a total of 31 secondary neoplasms involving the testis: 14 at postmortem examination and 17 surgical specimens. Nine cases were leukaemias: six acute lymphoblastic and two acute myeloid leukaemias in children, and one chronic lymphocytic leukaemia in an adult. The commonest primary sites of metastases to the testis were prostate (six cases), stomach (five cases) and lung (three cases). There were two malignant melanomas and isolated examples of metastases from the adrenal gland (neuroblastoma), cerebellum (medulloblastoma), soft tissue (alveolar rhabdomyosarcoma), pancreas and rectum. Of the metastases from solid tumours, 12 involved the right testis only, three involved the left and four were bilateral. In seven of these cases there were multiple testicular nodules, in seven there was a single mass, and in the rest there was diffuse involvement. Secondary neoplasms represented 4.6% of all testicular neoplasms at autopsy, and 1.6% in surgical specimens. There were five secondary penile neoplasms: two each from the pancreas and prostate and one from the bladder. Two neoplasms metastatic to the spermatic cord, both from a gastric primary, were included in the series. CONCLUSIONS Secondary neoplasms of the testis occur with a frequency comparable to other sites in the genitourinary tract, and metastases to the spermatic cord, epididymis, and penis, are rare in comparison. Disseminated neoplasms rarely present initially at this site and are histologically distinctive in adults, but in children they must be distinguished from primary small round blue cell tumours.
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Affiliation(s)
- N Dutt
- Department of Histopathology and Morbid Anatomy, Institute of Pathology, The Royal London Hospital, London, UK
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33
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Köseoğlu V, Akata D, Kutluk T, Yalçin B, Arat A, Sökmensüer C, Büyükpamukçu M. Neuroblastoma with spermatic cord metastasis in a child: sonographic findings. JOURNAL OF CLINICAL ULTRASOUND : JCU 1999; 27:287-289. [PMID: 10355894 DOI: 10.1002/(sici)1097-0096(199906)27:5<287::aid-jcu10>3.0.co;2-s] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 05/23/2023]
Abstract
We report a case of neuroblastoma in a patient who had no involvement of the spermatic cord at diagnosis but who developed spermatic cord metastasis 2 months later. The metastasis appeared on sonography as a hypoechoic, highly vascular, fusiform, hard, 14x10x7 mm mass located in the right inguinal canal and extending into the scrotum. The diagnosis of spermatic cord metastasis was confirmed by resection and histopathologic examination. We recommend that the scrotum and spermatic cord be evaluated by high-resolution sonography in children with neuroblastoma, both at the time of diagnosis and during follow-up.
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Affiliation(s)
- V Köseoğlu
- Department of Pediatric Oncology, Hacettepe University, Institute of Oncology, Ankara, Turkey
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Rashid AM, Williams RM, Malone PR. Metastatic appendiceal carcinoma masquerading as spermatic cord tumour. BRITISH JOURNAL OF UROLOGY 1993; 72:386-7. [PMID: 8221008 DOI: 10.1111/j.1464-410x.1993.tb00745.x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 01/29/2023]
Affiliation(s)
- A M Rashid
- Department of Histopathology, Royal Berkshire Hospital, Reading
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35
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Nistal M, Iñiguez L, Paniagua R, Redondo E. Paratesticular metastases from congenital retroperitoneal tumor. Urology 1989; 33:131-4. [PMID: 2916286 DOI: 10.1016/0090-4295(89)90011-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/03/2023]
Abstract
A retroperitoneal tumor was removed from a fifteen-day-old infant. Light microscopy revealed a teratoma consisting mainly of immature nervous tissue. Three months later the patient had recurrence and numerous peritoneal metastases showing a histologic pattern similar to that of the primary tumor. Twelve months later there was enlargement of the left testis due to metastases from teratoma infiltrating the tunica vaginalis of the left testis, the epididymis, and the spermatic cord. These metastases consisted of mature neurons and glial cells. The early dissemination of the tumor suggests an intracavitary spread pattern. The tumor maturation in paratesticular structures suggests that mesothelial cells are involved in the differentiation of tumoral germ cells.
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Affiliation(s)
- M Nistal
- Department of Morphology, School of Medicine, Autonomous University of Madrid, Spain
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36
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Abstract
A case of ureteral transitional cell carcinoma metastasizing to ipsilateral spermatic cord is reported.
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Affiliation(s)
- Y Komeda
- Department of Urology, Chusei General Hospital, Mie Prefecture, Japan
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