Tewary K, Narchi H. Recurrent urinary tract infections in children: Preventive interventions other than prophylactic antibiotics. World J Methodol 2015; 5(2): 13-19 [PMID: 26140267 DOI: 10.5662/wjm.v5.i2.13]
Corresponding Author of This Article
Hassib Narchi, MD, FRCPCH, Department of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, PO Box 17666, United Arab Emirates. hassib.narchi@uaeu.ac.ae
Research Domain of This Article
Pediatrics
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Methodol. Jun 26, 2015; 5(2): 13-19 Published online Jun 26, 2015. doi: 10.5662/wjm.v5.i2.13
Recurrent urinary tract infections in children: Preventive interventions other than prophylactic antibiotics
Kishor Tewary, Hassib Narchi
Kishor Tewary, Department of Pediatrics, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG Staffordshire, United Kingdom
Hassib Narchi, Department of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, PO Box 17666, United Arab Emirates
Author contributions: Tewary K and Narchi H had made substantial contributions to the conception and design of the editorial, drafting the article or making critical revisions related to important intellectual content of the manuscript and final approval of the version of the article to be published.
Conflict-of-interest: The authors have no commercial, personal, political, intellectual, or religious conflict-of-interest to report in relation to this work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hassib Narchi, MD, FRCPCH, Department of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, PO Box 17666, United Arab Emirates. hassib.narchi@uaeu.ac.ae
Telephone: +971-37-137414 Fax: +971-37-672022
Received: January 19, 2015 Peer-review started: January 20, 2015 First decision: February 7, 2015 Revised: March 3, 2015 Accepted: April 16, 2015 Article in press: April 20, 2015 Published online: June 26, 2015 Processing time: 169 Days and 5.8 Hours
Core Tip
Core tip: Antibiotic prophylaxis against urinary tract infection recurrences is associated with adverse drug reaction and development of resistance. Although showing some promise, alternative interventions, such as Vaccinium Macrocarpon (cranberry), Lactobacillus and Probiotics, circumcision, surgical management of vesicoureteral reflux, deliberate colonization of the urinary tract with Escherichia-coli (E. coli) 83972, treating constipation and dysfunctional voiding, administration of synthetic substitutes that reproduce natural surface glycosaminoglycan(s) anti-adherence effect on uroepithelial cells and E. coli isolate NU14 DeltawaaL as a candidate for developing a live-attenuated vaccine, do not provide so far a definitive effective answer. Further high quality research is still required.
