Dental movement acceleration: Literature review by an alternative scientific evidence method

Core Tip

Core tip: Orthodontic systematic reviews of randomized clinical trials, meta analysis and meta analysis network are difficult to develop due to a lack of high quality randomized clinical trials related to orthodontic therapies. The correct classification of the scientific literature following the evidence-based hierarchy facilitates the answers to specific clinical questions, and thus its application in every scientific subject. The resources available to speed up orthodontic movement had been widely examined. Due to a lack of evidence-based strength, the latter method cannot be taken into account in clinical protocols, thus we are left with the main already clinically proven methods: local injection of cellular mediators, physical stimuli, and surgically assisted orthodontics.