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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Sep 20, 2025; 15(3): 100840
Published online Sep 20, 2025. doi: 10.5662/wjm.v15.i3.100840
Published online Sep 20, 2025. doi: 10.5662/wjm.v15.i3.100840
The remarkable effects of the ionized medical water Asea® in 3 boys with Duchenne dystrophy: Three case reports
Andrei-Lucian Drăgoi, Roxana-Maria Nemeș, Medical Doctoral School, University of "Titu Maiorescu", Targoviste 130056, Romania
Author contributions: Drăgoi AL designed, analyzed, interpreted and prepared the manuscript; Nemeș RM initially reviewed the manuscript and provided essential feedback.
Informed consent statement: All parents of the 3 DMD boys provided their consent to publish these clinical cases without any personal identification details.
Conflict-of-interest statement: The authors of this paper declare no existing competing interests. The authors of this paper do not hold any positions in any commercial companies that sell Asea®.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andrei-Lucian Drăgoi, MD, Doctor, Researcher, Medical Doctoral School of University "Titu Maiorescu", Str. General I. E. Florescu nr. 9, Targoviste 130056, Romania. dr.dragoi@yahoo.com
Received: August 28, 2024
Revised: October 26, 2024
Accepted: December 11, 2024
Published online: September 20, 2025
Processing time: 190 Days and 11 Hours
Revised: October 26, 2024
Accepted: December 11, 2024
Published online: September 20, 2025
Processing time: 190 Days and 11 Hours
Core Tip
Core Tip: Asea redox supplement has significant indirect antioxidant effects via NRF2. Based on the case studies here, extensive trials should be initiated in children with Duchenne muscular dystrophy (DMD) as an adjuvant to corticoids or as a substitute in DMD patients who refuse corticoids. Because of its antioxidant effects, it should also be studied as an adjuvant in many types of acute/chronic infectious/non-infectious diseases in which cellular oxidative stress is involved.