Echo contrast medium: How the use of contrast echocardiography (ultrasound contrast agents) can improve patient care

doi:10.5662/wjm.v15.i3.100490

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Sep 20, 2025 (publication date) through Mar 6, 2025

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Sep 20, 2025; 15(3): 100490
Published online Sep 20, 2025. doi: 10.5662/wjm.v15.i3.100490

Echo contrast medium: How the use of contrast echocardiography (ultrasound contrast agents) can improve patient care

Kevan English

Kevan English, Department of Internal Medicine, University of Nebraska Medical Center College of Medicine, Omaha, NE 68198, United States

Author contributions: English K wrote the original draft; English K contributed to conceptualization, writing, reviewing, and editing; English K read and approved the final version of the manuscript.

Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Kevan English, MD, Department of Internal Medicine, University of Nebraska Medical Center College of Medicine, S 42^nd & Emile St, Omaha, NE 68198, United States. keenglish@unmc.edu

Received: August 18, 2024
Revised: December 14, 2024
Accepted: December 20, 2024
Published online: September 20, 2025
Processing time: 200 Days and 4.8 Hours

Core Tip

Core Tip: The use of ultrasound contrast agents (UCAs) during resting echocardiography can improve diagnostic accuracy by adequately assessing left ventricular (LV) function. Compared to standard echocardiograms, UCAs, when used, allow physicians to better assess regional wall motion abnormalities and LV ejection fraction. As a result, patients with LV apex disease can be accurately diagnosed without additional imaging. This consequently shortens hospital stays and improves patient outcomes.