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World J Methodol. Sep 20, 2024; 14(3): 89761
Published online Sep 20, 2024. doi: 10.5662/wjm.v14.i3.89761
COVID-19 mutations: An overview
Malay Sarkar, Irappa Madabhavi
Malay Sarkar, Department of Pulmonary Medicine, Indira Gandhi Medical College, Shimla 171001, Himachal Pradesh, India
Irappa Madabhavi, Department of Medical and Pediatric Oncology and Hematology, J N Medical College, and KAHER, Belagavi, Karnataka 590010, India
Irappa Madabhavi, Department of Medical and Pediatric Oncology and Hematology, Kerudi Cancer Hospital, Bagalkot, Karnataka 587103, India
Author contributions: Sarkar M conceived and designed the experiment, made critical revisions, and approved the final version; Madabhavi I and Sarkar M analyzed the previous studies and research and wrote the first draft of the manuscript, contributed to the writing of the manuscript, jointly developed the structure and arguments for the paper. All authors reviewed and approved the final manuscript.
Conflict-of-interest statement: Authors declare no conflicts of interest while publishing this research work.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Noncommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Irappa Madabhavi, MBBS, MD, DM, ECMO. Consultant Physician-Scientist, Department of Medical and Pediatric Oncology and Hematology, J N Medical College, and KAHER, Belagavi, Karnataka 590010, India. irappamadabhavi@gmail.com
Received: November 12, 2023
Revised: February 7, 2024
Accepted: April 17, 2024
Published online: September 20, 2024
Processing time: 226 Days and 4.5 Hours
Core Tip

Core Tip: The severe acute respiratory syndrome coronavirus-2 virus is constantly evolving because to natural immunity and vaccine-induced immunity which exert continual immunological pressure, resulting in the generation of newer variants and numerous new mutations. This study detailed the many variants of concern (VOCs), including their transmissibility, severity, and immune-evasion capacities. We have also discussed several key mutations and their consequences. The tables summarized the major points of the paper and provided a full discussion of the important mutations found in these VOCs. Readers will benefit from our article's concise overview of these areas.