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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Sep 20, 2023; 13(4): 296-322
Published online Sep 20, 2023. doi: 10.5662/wjm.v13.i4.296
Published online Sep 20, 2023. doi: 10.5662/wjm.v13.i4.296
Post-COVID-19 cholangiopathy: Systematic review
Mazen Abdalla Rasheed, Jonathan Soldera, Acute Medicine, University of South Wales, Cardiff CF37 1DL, United Kingdom
Vinícius Remus Ballotin, Lucas Goldmann Bigarella, School of Medicine, Universidade de Caxias do Sul, Caxias do Sul 95070-560, Brazil
Author contributions: All authors contributed to the study concept and design, drafting of the manuscript, data acquisition, analysis and interpretation, and critical revision of the manuscript for important intellectual content.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jonathan Soldera, MD, MSc, Tutor, Acute Medicine, University of South Wales, 86-88 Adam St, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com
Received: April 15, 2023
Peer-review started: April 15, 2023
First decision: May 12, 2023
Revised: June 7, 2023
Accepted: August 23, 2023
Article in press: August 23, 2023
Published online: September 20, 2023
Processing time: 157 Days and 12.8 Hours
Peer-review started: April 15, 2023
First decision: May 12, 2023
Revised: June 7, 2023
Accepted: August 23, 2023
Article in press: August 23, 2023
Published online: September 20, 2023
Processing time: 157 Days and 12.8 Hours
Core Tip
Core Tip: Post-coronavirus disease 2019 (COVID-19) cholangiopathy is a rare but serious complication that can occur after contracting COVID-19. It is characterized by inflammation and damage to the bile ducts. To better understand this condition and its treatment, we conducted a systematic review of post-COVID-19 cholangiopathy cases. Sixty-three articles met the inclusion criteria, representing 540 patients. Males over 50-years-old were more prone to this condition, which is often accompanied by elevated liver function, bile duct thickening, and kidney failure after prolonged use of mechanical ventilation. Further research is needed to confirm the effectiveness of liver transplantation in treating post-COVID-19 cholangiopathy.