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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Jun 20, 2023; 13(3): 79-97
Published online Jun 20, 2023. doi: 10.5662/wjm.v13.i3.79
Published online Jun 20, 2023. doi: 10.5662/wjm.v13.i3.79
Immunotherapy for advanced gastric cancer
Wattana Leowattana, Pathomthep Leowattana, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Rachatawee 10400, Bangkok, Thailand
Tawithep Leowattana, Department of Medicine, Faculty of Medicine, Srinakharinwirot University, Wattana 10110, Bangkok, Thailand
Author contributions: Leowattana W wrote the paper; Leowattana T and Leowattana P collected the data.
Conflict-of-interest statement: The authors declare no conflicts of interest related to this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wattana Leowattana, BMed, MD, MSc, PhD, Full Professor, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420/6 Rajavithi road, Tungphyathai, Rachatawee 10400, Bangkok, Thailand.
Received: April 1, 2023
Peer-review started: April 1, 2023
First decision: May 4, 2023
Revised: May 11, 2023
Accepted: May 31, 2023
Article in press: May 31, 2023
Published online: June 20, 2023
Processing time: 80 Days and 3.9 Hours
Peer-review started: April 1, 2023
First decision: May 4, 2023
Revised: May 11, 2023
Accepted: May 31, 2023
Article in press: May 31, 2023
Published online: June 20, 2023
Processing time: 80 Days and 3.9 Hours
Core Tip
Core Tip: Throughout the globe, gastric cancer (GC) is ranked as the fifth most frequent cancer and the third most common cause of death. Chemotherapy, radiation, stomach resection, and targeted treatments are common treatment modalities. The development of immunotherapy for GC has already produced some encouraging outcomes and changed the treatment process. Currently, new immunotherapies that target novel molecules, as well as other combination treatments, have been developed. Immune checkpoint inhibitors are being used more and more often. In this review, we sought to examine the viewpoint, development, and reported clinical results of several immunotherapy treatment modalities for advanced GC patients.