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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Methodol. Jun 20, 2023; 13(3): 46-58
Published online Jun 20, 2023. doi: 10.5662/wjm.v13.i3.46
Published online Jun 20, 2023. doi: 10.5662/wjm.v13.i3.46
Evolving utility of exosomes in pancreatic cancer management
Thattungal Manoharan Anoop, Ajai Thomas, S Manoj, Department of Medical Oncology, Regional Cancer Center, Medical College Campus, Thiruvananthapuram 695011, Kerala, India
Palash Kumar Basu, Department of Avionics, Indian Institute of Space Science & Technology (IIST), Thiruvananthapuram 695547, Kerala, India
K Chandramohan, Surgical Oncology, Regional Cancer Center, Thiruvananthapuram 695011, Kerala, India
Author contributions: Anoop TM designed the study, drafted the manuscript; Basu PK participated in the design and draft of the manuscript; Chandramohan K participated in the design and draft of the manuscript; Thomas A participated in the design and draft of the manuscript; Manoj S participated in the design and draft of the manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Thattungal Manoharan Anoop, MBBS, MD, DM, DNB, FRCP Edin, Associate Professor, Department of Medical Oncology, Regional Cancer Center, Medical Coldranooptm@yahoo.co.in
Received: March 22, 2023
Peer-review started: March 22, 2023
First decision: April 17, 2023
Revised: May 2, 2023
Accepted: May 31, 2023
Article in press: May 31, 2023
Published online: June 20, 2023
Processing time: 89 Days and 19.3 Hours
Peer-review started: March 22, 2023
First decision: April 17, 2023
Revised: May 2, 2023
Accepted: May 31, 2023
Article in press: May 31, 2023
Published online: June 20, 2023
Processing time: 89 Days and 19.3 Hours
Core Tip
Core Tip: The determination and identification of biomarkers using liquid biopsy can enable the early detection, monitoring, therapeutic interventions, risk of relapse, therapeutic targets and identification of resistance mechanisms in pancreatic cancer (PC). There has been a recent interest in use of exosomes as biomarker in PC management. Exosomes loaded with multiple diagnostic molecules can be isolated from different body fluids and can be used for making the exosome markers-based liquid biopsy more attractive for initial tumor detection, monitoring, and prognostic assessment of PC.