Binay UD, Karavaş E, Karakeçili F, Barkay O, Aydin S, Şenbil DC. Effect of vaccination status on CORADS and computed tomography severity score in hospitalized COVID-19 patients: A retrospective study. World J Methodol 2023; 13(5): 456-465 [PMID: 38229950 DOI: 10.5662/wjm.v13.i5.456]
Corresponding Author of This Article
Umut Devrim Binay, MD, Assistant Professor, Department of Infectious Diseases and Clinical Microbiology, Erzincan Binali Yildirim University, Faculty of Medicine, Başbağlar Mahallesi, Hacı Ali Akın Sokağı, Erzincan 24000, Turkey. umut.binay@erzincan.edu.tr
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Methodol. Dec 20, 2023; 13(5): 456-465 Published online Dec 20, 2023. doi: 10.5662/wjm.v13.i5.456
Effect of vaccination status on CORADS and computed tomography severity score in hospitalized COVID-19 patients: A retrospective study
Umut Devrim Binay, Erdal Karavaş, Faruk Karakeçili, Orçun Barkay, Sonay Aydin, Düzgün Can Şenbil
Umut Devrim Binay, Faruk Karakeçili, Orçun Barkay, Department of Infectious Diseases and Clinical Microbiology, Erzincan Binali Yildirim University, Faculty of Medicine, Erzincan 24000, Turkey
Erdal Karavaş, Department of Radiology, Bandırma 17 Eylül University, Faculty of Medicine, Balıkesir 10200, Turkey
Sonay Aydin, Düzgün Can Şenbil, Department of Radiology, Erzincan Binali Yıldırım University, Faculty of Medicine, Erzincan 24000, Turkey
Author contributions: Binay UD designed and performed the research and wrote the manuscript; Karavas E designed the research and supervised the report; Karakeçili F designed the research and contributed to the analysis; Barkay O, Aydin S, Senbil DC provided clinical advice; Barkay O, Aydin S, Senbil DC supervised the report. All authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Erzincan Binali Yildirim University Ethics Committee (Approval No: 04/16).
Informed consent statement: Since it is a retrospective study, patient consent was not obtained.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Data sharing statement: Data will be shared upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Umut Devrim Binay, MD, Assistant Professor, Department of Infectious Diseases and Clinical Microbiology, Erzincan Binali Yildirim University, Faculty of Medicine, Başbağlar Mahallesi, Hacı Ali Akın Sokağı, Erzincan 24000, Turkey. umut.binay@erzincan.edu.tr
Received: September 27, 2023 Peer-review started: September 27, 2023 First decision: November 2, 2023 Revised: November 6, 2023 Accepted: December 7, 2023 Article in press: December 7, 2023 Published online: December 20, 2023
ARTICLE HIGHLIGHTS
Research background
The coronavirus disease 2019 (COVID-19) pandemic is still continuing. Vaccination has an important place in preventing the disease and vaccination reduces the possibility of a severe course of the disease.
Research motivation
It is important to investigate whether vaccination has any effect on the computed tomography (CT) severity score (CT-SS) and CORADS score of COVID-19 patients.
Research objectives
We aim to investigate whether the vaccination status of inpatient treatment for COVID-19 has any effect on the CT-SS and CORADS score taken during hospitalization.
Research methods
This single-center retrospective study was conducted between April 1, 2021 and April 1, 2022 with a total of 224 patients older than 18 years of age, whose vaccination status was accessible, who had positive severe acute respiratory syndrome coronavirus 2 polymerase chain reaction results, and who had a thorax CT taken during hospitalization.
Research results
Among the patients included in the study, 52.2% were female and the mean age was 61.85 years. The patients applied to the hospital on the average 7th day of their complaints. While 63 patients were unvaccinated (Group 1), 20 were vaccinated with a single dose of CoronaVac (Group 2), 24 with a single dose of BioNTech (Group 3), 38 with 2 doses of CoronaVac (Group 4), 40 with 2 doses of BioNTech (Group 5), and 39 with 3 doses of vaccine (2 doses of CoronaVac followed by a single dose of BioNTech, Group 6). CT-SS ranged from 5 to 23, with a mean of 12.17. CT-SS mean of the groups were determined as 14.17, 13.35, 11.58, 10.87, 11.28, 10.85, respectively. Accordingly, as a result of the comparisons between the groups, the CT-SS levels of the unvaccinated patients found to be significantly higher than the other groups. As the vaccination rates increased, the rate of typical COVID-19 findings on CT was found to be significantly lower.
Research conclusions
The increase in vaccination rates in COVID-19 patients reduces the CT Severity Score and the CORADS score.
Research perspectives
It is important that COVID-19 vaccinations continue. With the effect of vaccination, the possibility of severe course of the disease will decrease. There will be a need for studies in which more patient data are analyzed and data obtained from patients with different vaccines are evaluated.
