Paniccia R, Priora R, Liotta AA, Maggini N, Abbate R. Assessment of platelet function: Laboratory and point-of-care methods. World J Transl Med 2014; 3(2): 69-83 [DOI: 10.5528/wjtm.v3.i2.69]
Corresponding Author of This Article
Rita Paniccia, MSc, Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Viale Pieraccini, 19, 50134 Florence, Italy. rita.paniccia@unifi.it
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Rita Paniccia, Raffaella Priora, Rosanna Abbate, Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, 50134 Florence, Italy
Rita Paniccia, Raffaella Priora, Agatina Alessandrello Liotta, Niccolò Maggini, Rosanna Abbate, Department of Heart and Vessels, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy
Author contributions: Paniccia R conceived and designed the review, prepared the manuscript and searched literature; Priora R contributed to literature review and preparation of the manuscript; Alessandrello Liotta A and Maggini N contributed to editing and finalizing the manuscript; Abbate R approved of the version to be published.
Correspondence to: Rita Paniccia, MSc, Department of Experimental and Clinical Medicine, Thrombosis Center, University of Florence, Viale Pieraccini, 19, 50134 Florence, Italy. rita.paniccia@unifi.it
Telephone: +39-055-7949419 Fax: +39-055-7949929
Received: January 2, 2014 Revised: March 14, 2014 Accepted: April 25, 2014 Published online: August 12, 2014 Processing time: 237 Days and 18.7 Hours
Core Tip
Core tip: This review discussed the scenario of available platelet function laboratory and point-of-care methods suitable in different clinical setting. As this matter has become of crucial importance in the bleeding management and for monitoring antiplatelet therapies, improved ability to assess platelet function in a timely and efficient manner is essential. Traditional platelet function methods, requiring a fair degree of expertise, have been limited to specialized laboratory. Many efforts have been carried out for improving platelet function assays for centralized laboratory, such as different point-of-care testing methodologies have been developed. Moreover, different guidelines and recommendations for their method standardization are growing.
