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World J Transl Med. Dec 12, 2013; 2(3): 49-55
Published online Dec 12, 2013. doi: 10.5528/wjtm.v2.i3.49
Published online Dec 12, 2013. doi: 10.5528/wjtm.v2.i3.49
Impact of viral and bacterial infections in coronary artery disease patients
Hem Chandra Jha, Aruna Mittal, National Institute of Pathology-ICMR, New Delhi 110029, India
Hem Chandra Jha, Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, United States
Author contributions: Jha HC, Mittal A solely contributed to this paper.
Correspondence to: Aruna Mittal, Consultant, National Institute of Pathology-ICMR, New Delhi 110029, India. amittal_iop@yahoo.com
Telephone: +91-11-26198402 Fax: +91-11-2619801
Received: August 16, 2013
Revised: September 30, 2013
Accepted: November 1, 2013
Published online: December 12, 2013
Processing time: 142 Days and 22.1 Hours
Revised: September 30, 2013
Accepted: November 1, 2013
Published online: December 12, 2013
Processing time: 142 Days and 22.1 Hours
Core Tip
Core tip: This paper describes the association of atherosclerosis with different infectious agents, specifically Chlamydia pneumoniae (C. pneumoniae), Helicobacter pylori, Herpes viruses and periodontal pathogens. There are many other bacteria and viruses, as well as life style related factors described and cited in this review. The manuscript also emphasizes how C. pneumoniae is modulating the human immune system with mimicking some antigenic proteins of the host. Overall, this report helps in the field of cardiac biology to explore associated risk factors in more detail.