Podocyturia: Potential applications and current limitations

Figure 1 Glomerular filtration barrier. The podocyte with two of its many foot processes are attached to the glomerular basement membrane forming the slit diaphragm. Some components of these structures are illustrated. The fenestrated endothelium is depicted next to the basement membrane. TRPC6: Transient receptor potential cation channel 6; uPAR: Urokinase-type plasminogen activator receptor.

Figure 2 A cluster of podocytes diagnosed by immunofluorescence in a patient with Fabry disease are shown to the right (white arrow). Synaptopodin has been employed as the targeted podocyte protein. Tubular cells are also seen to the left of the image (yellow arrow). Green color stands for cytoplasmic synaptopodin, while blue color discloses cellular nuclei × 400.