Copyright
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Sep 6, 2017; 6(5): 221-228
Published online Sep 6, 2017. doi: 10.5527/wjn.v6.i5.221
Published online Sep 6, 2017. doi: 10.5527/wjn.v6.i5.221
Podocyturia: Potential applications and current limitations
Hernán Trimarchi, Nephrology Service, Hospital Británico de Buenos Aires, Buenos Aires 1280AEB, Argentina
Author contributions: Trimarchi H wrote the manuscript.
Conflict-of-interest statement: The author declares no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hernán Trimarchi, MD, PhD, Nephrology Service, Hospital Británico de Buenos Aires, Perdriel 74, Buenos Aires 1280AEB, Argentina. cenefrologia@hbritanico.com.ar
Telephone: +54-11-43096400 Fax: +54-11-43096400-2551
Received: March 25, 2017
Peer-review started: March 28, 2017
First decision: May 4, 2017
Revised: July 18, 2017
Accepted: July 21, 2017
Article in press: July 23, 2017
Published online: September 6, 2017
Processing time: 159 Days and 22.7 Hours
Peer-review started: March 28, 2017
First decision: May 4, 2017
Revised: July 18, 2017
Accepted: July 21, 2017
Article in press: July 23, 2017
Published online: September 6, 2017
Processing time: 159 Days and 22.7 Hours
Core Tip
Core tip: Podocytes are cells that do not proliferate under normal conditions. Their loss in the urine, a process known as podocyturia, antedates proteinuria. When the number of podocytes per glomerulus is less than 80%, glomerulosclerosis is triggered and if not stopped, it will eventually lead to chronic kidney failure and end-stage kidney disease. A prompt and standardized assessement of podocyturia should lead to better results related to glomerular disease outcomes.