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World J Nephrol. Nov 6, 2014; 3(4): 295-301
Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.295
Figure 1
Figure 1 Species difference in angiotensin II/nitric oxide signalling in proximal tubules. In humans, NO/cGMP stimulates PT transport via ERK. In mouse, by contrast, NO/cGMP inhibits PT transport via cGKII. Ang II: Angiotensin II; NO: Nitric oxide; cGMP: Guanosine 3’,5’-cyclic monophosphate; ERK: Extracellular signal-regulated kinase.