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World J Nephrol. Jun 30, 2020; 9(1): 1-8
Published online Jun 30, 2020. doi: 10.5527/wjn.v9.i1.1
Renal transplant recipient seizure practical management
Harpreet Sawhney, Simon S Gill
Harpreet Sawhney, Department of Nephrology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London W12 0HS, United Kingdom
Simon S Gill, Department of Radiology, Frimley Health NHS Foundation Trust, Slough, Berkshire SL2 4HL, United Kingdom
Author contributions: Sawhney H was involved in writing the original draft, read and approved the final manuscript; and Gill SS was involved in writing the original draft, read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Harpreet Sawhney, MA(Cantab) MBBS, MRCP, Doctor, Department of Nephrology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, United Kingdom. harpreet.sawhney@doctors.org.uk
Received: December 2, 2019
Peer-review started: December 2, 2019
First decision: December 11, 2019
Revised: May 23, 2020
Accepted: June 10, 2020
Article in press: June 10, 2020
Published online: June 30, 2020
Processing time: 208 Days and 10.4 Hours
Core Tip

Core tip: For selection of an antiepileptic drug (AED) in renal transplant patients: it should be a non-enzyme inducer; its metabolism and excretion should not be affected by renal failure; there are minimal dose adjustments with haemodialysis; the loading dose of most AED remain the same in renal impairment; and, sodium valproate is a good choice for an antiepileptic drug in renal transplant patients.